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Polr2g Gene Detail
Summary
  • Symbol
    Polr2g
  • Name
    polymerase (RNA) II (DNA directed) polypeptide G
  • Synonyms
    2410046K11Rik, A230108L04Rik, RBP7, Rpo2-7l
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914960
    NCBI Gene: 67710
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:8770493-8775921 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 5.62 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    188 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914960
 protein coding gene Chr19:8770491-8775941 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024809
 protein coding gene Chr19:6074189-6079576 (-)
A/J MGP_AJ_G0024777
 protein coding gene Chr19:5745568-5750747 (-)
AKR/J MGP_AKRJ_G0024752
 protein coding gene Chr19:5836616-5841985 (-)
BALB/cJ MGP_BALBcJ_G0024777
 protein coding gene Chr19:5850023-5855237 (-)
C3H/HeJ MGP_C3HHeJ_G0024543
 protein coding gene Chr19:5915814-5923056 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025224
 protein coding gene Chr19:6194255-6199866 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022653
 protein coding gene Chr19:5990771-5996415 (-)
CAST/EiJ MGP_CASTEiJ_G0024016
 protein coding gene Chr19:5566600-5572898 (-)
CBA/J MGP_CBAJ_G0024517
 protein coding gene Chr19:6312953-6319654 (-)
DBA/2J MGP_DBA2J_G0024644
 protein coding gene Chr19:5576371-5582530 (-)
FVB/NJ MGP_FVBNJ_G0024611
 protein coding gene Chr19:5650530-5656515 (-)
LP/J MGP_LPJ_G0024731
 protein coding gene Chr19:5960019-5966234 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024638
 protein coding gene Chr19:6178537-6184968 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025273
 protein coding gene Chr19:5878686-5884243 (-)
PWK/PhJ MGP_PWKPhJ_G0023761
 protein coding gene Chr19:5246123-5251422 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023566
 protein coding gene Chr19:5485619-5491531 (-)
WSB/EiJ MGP_WSBEiJ_G0024078
 protein coding gene Chr19:5848811-5854015 (-)



Homology
more
  • Human Ortholog
    POLR2G, RNA polymerase II subunit G
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    POLR2G, RNA polymerase II subunit G
  • Synonyms
    hRPB19, hsRPB7, RPB19, RPB7
  • Links
    NCBI Gene ID: 5436
    neXtProt AC: NX_P62487
    UniProt: P62487

  • Chr Location
    11q12.3; chr11:62761565-62766710 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    812
  • Tissues
    106
  • cDNA Data
    90
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 67710 NCBI Gene Model | MGI Sequence Detail 5429 C57BL/6J ±  kb
transcript NM_026329 RefSeq | MGI Sequence Detail 868 C57BL/6  
polypeptide P62488 UniProt | EBI | MGI Sequence Detail 172 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 92
    cDNA 92

    Microarray probesets 4
Other
Accession IDs
less
MGI:1100536, MGI:1925681, MGI:2147773
References
more
  • Summaries
    All 38
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:6800 Monaco JJ, et al., Identification of a fourth class of proteins linked to the murine major histocompatibility complex. Proc Natl Acad Sci U S A. 1982 May;79(9):3001-5
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory