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Slc39a13 Gene Detail
Summary
  • Symbol
    Slc39a13
  • Name
    solute carrier family 39 (metal ion transporter), member 13
  • Synonyms
    1100001L14Rik, ZIP13
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915677
    NCBI Gene: 68427
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:90892136-90900754 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 50.44 cM, cytoband E1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    246 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915677
 protein coding gene Chr2:90892136-90900762 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026140
 protein coding gene Chr2:92362527-92371101 (-)
A/J MGP_AJ_G0026101
 protein coding gene Chr2:88669088-88677903 (-)
AKR/J MGP_AKRJ_G0026082
 protein coding gene Chr2:91122630-91132069 (-)
BALB/cJ MGP_BALBcJ_G0026110
 protein coding gene Chr2:88834179-88842965 (-)
C3H/HeJ MGP_C3HHeJ_G0025861
 protein coding gene Chr2:91398845-91408504 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026561
 protein coding gene Chr2:95619996-95626218 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023952
 protein coding gene Chr2:85186794-85195398 (-)
CAST/EiJ MGP_CASTEiJ_G0025326
 protein coding gene Chr2:91922499-91931026 (-)
CBA/J MGP_CBAJ_G0025839
 protein coding gene Chr2:98868566-98879525 (-)
DBA/2J MGP_DBA2J_G0025975
 protein coding gene Chr2:88267768-88276394 (-)
FVB/NJ MGP_FVBNJ_G0025938
 protein coding gene Chr2:87374257-87383027 (-)
LP/J MGP_LPJ_G0026079
 protein coding gene Chr2:92569625-92582039 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025964
 protein coding gene Chr2:101910190-101922095 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026615
 protein coding gene Chr2:91180779-91190699 (-)
PWK/PhJ MGP_PWKPhJ_G0025061
 protein coding gene Chr2:87996480-88005165 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024862
 protein coding gene Chr2:90764072-90771674 (-)
WSB/EiJ MGP_WSBEiJ_G0025393
 protein coding gene Chr2:91772934-91783895 (-)



Homology
more
  • Human Ortholog
    SLC39A13, solute carrier family 39 member 13
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC39A13, solute carrier family 39 member 13
  • Synonyms
    EDSSPD3, LZT-Hs9, SCDEDS, ZIP13
  • Links
    NCBI Gene ID: 91252
    neXtProt AC: NX_Q96H72
    UniProt: Q96H72

  • Chr Location
    11p11.2; chr11:47407132-47416500 (+)  GRCh38
Human Diseases
more
  • Diseases
    2 with human SLC39A13 associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    29 phenotypes from 1 allele in 1 genetic background
    2 images
    24 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for disruption of this gene display skeletal abnormalities and dental abnormalities.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    27
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    46
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 68427 NCBI Gene Model | MGI Sequence Detail 8619 C57BL/6J ±  kb
    transcript NM_001290765 RefSeq | MGI Sequence Detail 2315 C57BL/6  
    polypeptide Q8BZH0 UniProt | EBI | MGI Sequence Detail 361 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 46
      cDNA 46

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:3035256
    References
    more
    • Summaries
      All 52
      Developmental Gene Expression 1
      Gene Ontology 7
      Phenotypes 24
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:330194 Hara T, et al., Role of Scl39a13/ZIP13 in cardiovascular homeostasis. PLoS One. 2022;17(10):e0276452
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/05/2024
    MGI 6.24     		The Jackson Laboratory