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Ube2c Gene Detail
Summary
  • Symbol
    Ube2c
  • Name
    ubiquitin-conjugating enzyme E2C
  • Synonyms
    1110015A16Rik, D2Ertd695e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915862
    NCBI Gene: 68612
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:164611849-164614822 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 85.27 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    196 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915862
 protein coding gene Chr2:164611818-164620742 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026871
 protein coding gene Chr2:170267397-170276638 (+)
A/J MGP_AJ_G0026838
 protein coding gene Chr2:163308551-163317407 (+)
AKR/J MGP_AKRJ_G0026809
 protein coding gene Chr2:168162597-168171620 (+)
BALB/cJ MGP_BALBcJ_G0026847
 protein coding gene Chr2:163667366-163676222 (+)
C3H/HeJ MGP_C3HHeJ_G0026589
 protein coding gene Chr2:168526263-168535187 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027294
 protein coding gene Chr2:175198355-175207143 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024665
 protein coding gene Chr2:156714424-156723336 (+)
CAST/EiJ MGP_CASTEiJ_G0026047
 protein coding gene Chr2:168942430-168950976 (+)
CBA/J MGP_CBAJ_G0026566
 protein coding gene Chr2:181554662-181563473 (+)
DBA/2J MGP_DBA2J_G0026704
 protein coding gene Chr2:162474020-162482876 (+)
FVB/NJ MGP_FVBNJ_G0026670
 protein coding gene Chr2:160894736-160903592 (+)
LP/J MGP_LPJ_G0026806
 protein coding gene Chr2:170326036-170334519 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026689
 protein coding gene Chr2:185125015-185133498 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027351
 protein coding gene Chr2:168067440-168075923 (+)
PWK/PhJ MGP_PWKPhJ_G0025784
 protein coding gene Chr2:162074283-162083140 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025585
 protein coding gene Chr2:166966309-166974884 (+)
WSB/EiJ MGP_WSBEiJ_G0026120
 protein coding gene Chr2:168948729-168958511 (+)



Homology
more
  • Human Ortholog
    UBE2C, ubiquitin conjugating enzyme E2 C
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    UBE2C, ubiquitin conjugating enzyme E2 C
  • Synonyms
    dJ447F3.2, UBCH10
  • Links
    NCBI Gene ID: 11065
    neXtProt AC: NX_O00762
    UniProt: O00762

  • Chr Location
    20q13.12; chr20:45812576-45816957 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 2 alleles in 2 genetic backgrounds
    3 phenotypes from multigenic genotypes
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    39
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    725
  • Tissues
    18
  • cDNA Data
    74
  • Literature Summary
    10
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 68612 NCBI Gene Model | MGI Sequence Detail 2974 C57BL/6J ±  kb
transcript NM_026785 RefSeq | MGI Sequence Detail 931 ZRU/MplStud  
polypeptide Q9D1C1 UniProt | EBI | MGI Sequence Detail 179 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 75
    cDNA 74
    Primer pair 1

    Microarray probesets 2
Other
Accession IDs
less
MGI:1277160
References
more
  • Summaries
    All 51
    Developmental Gene Expression 10
    Gene Ontology 6
    Phenotypes 14
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:347974 Zhou B, et al., Identification of signaling pathways that specify a subset of migrating enteric neural crest cells at the wavefront in mouse embryos. Dev Cell. 2024 Apr 15;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory