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Mocs3 Gene Detail
Summary
  • Symbol
    Mocs3
  • Name
    molybdenum cofactor synthesis 3
  • Synonyms
    1700020H17Rik, Uba4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916622
    NCBI Gene: 69372
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:168072542-168074223 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 88.50 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    111 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916622
 protein coding gene Chr2:168072542-168074514 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026925
 protein coding gene Chr2:174061810-174064687 (+)
A/J MGP_AJ_G0026892
 protein coding gene Chr2:166863507-166865475 (+)
AKR/J MGP_AKRJ_G0026863
 protein coding gene Chr2:171842468-171844436 (+)
BALB/cJ MGP_BALBcJ_G0026901
 protein coding gene Chr2:167218665-167220640 (+)
C3H/HeJ MGP_C3HHeJ_G0026643
 protein coding gene Chr2:172212936-172214901 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027348
 protein coding gene Chr2:179143317-179145282 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024719
 protein coding gene Chr2:160167620-160169630 (+)
CAST/EiJ MGP_CASTEiJ_G0026101
 protein coding gene Chr2:172690642-172692602 (+)
CBA/J MGP_CBAJ_G0026620
 protein coding gene Chr2:185720924-185722889 (+)
DBA/2J MGP_DBA2J_G0026758
 protein coding gene Chr2:165963872-165965839 (+)
FVB/NJ MGP_FVBNJ_G0026724
 protein coding gene Chr2:164529907-164531881 (+)
LP/J MGP_LPJ_G0026859
 protein coding gene Chr2:174065474-174067434 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026743
 protein coding gene Chr2:189031126-189033135 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027405
 protein coding gene Chr2:171780165-171782132 (+)
PWK/PhJ MGP_PWKPhJ_G0025838
 protein coding gene Chr2:165654372-165656378 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025639
 protein coding gene Chr2:170738760-170740730 (+)
WSB/EiJ MGP_WSBEiJ_G0026174
 protein coding gene Chr2:172684435-172687819 (+)



Homology
more
  • Human Ortholog
    MOCS3, molybdenum cofactor synthesis 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MOCS3, molybdenum cofactor synthesis 3
  • Synonyms
    UBA4
  • Links
    NCBI Gene ID: 27304
    neXtProt AC: NX_O95396
    UniProt: O95396

  • Chr Location
    20q13.13; chr20:50958818-50963929 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    30
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    711
  • Tissues
    4
  • cDNA Data
    25
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 69372 NCBI Gene Model | MGI Sequence Detail 1682 C57BL/6J ±  kb
transcript NM_001160330 RefSeq | MGI Sequence Detail 1691 C57BL/6  
polypeptide A2BDX3 UniProt | EBI | MGI Sequence Detail 460 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 26
    cDNA 26

    Microarray probesets 3
References
more
  • Summaries
    All 29
    Developmental Gene Expression 1
    Gene Ontology 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:337087 Marelja Z, et al., The L-cysteine desulfurase NFS1 is localized in the cytosol where it provides the sulfur for molybdenum cofactor biosynthesis in humans. PLoS One. 2013;8(4):e60869
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory