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Fmo2 Gene Detail
Summary
  • Symbol
    Fmo2
  • Name
    flavin containing monooxygenase 2
  • Synonyms
    2310008D08Rik, 2310042I22Rik, MGC:28212
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916776
    NCBI Gene: 55990
  • Alliance
    gene page
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:162701886-162726295 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 70.34 cM, cytoband H1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    786 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916776
 protein coding gene Chr1:162701886-162726327 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016666
 protein coding gene Chr1:168242377-168272633 (-)
A/J MGP_AJ_G0016647
 protein coding gene Chr1:161380793-161405320 (-)
AKR/J MGP_AKRJ_G0016613
 protein coding gene Chr1:166271629-166301146 (-)
BALB/cJ MGP_BALBcJ_G0016608
 protein coding gene Chr1:161888494-161913671 (-)
C3H/HeJ MGP_C3HHeJ_G0016432
 protein coding gene Chr1:166467176-166493026 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017069
 protein coding gene Chr1:173878277-173905290 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014778
 protein coding gene Chr1:153414298-153438414 (-)
CAST/EiJ MGP_CASTEiJ_G0016012
 protein coding gene Chr1:166120135-166146022 (-)
CBA/J MGP_CBAJ_G0016407
 protein coding gene Chr1:180089478-180121390 (-)
DBA/2J MGP_DBA2J_G0016513
 protein coding gene Chr1:160306304-160331481 (-)
FVB/NJ MGP_FVBNJ_G0016511
 protein coding gene Chr1:158743065-158768200 (-)
LP/J MGP_LPJ_G0016584
 protein coding gene Chr1:169337767-169362257 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016536
 protein coding gene Chr1:187583731-187609335 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017105
 protein coding gene Chr1:166095806-166121170 (-)
PWK/PhJ MGP_PWKPhJ_G0015798
 protein coding gene Chr1:159493725-159519343 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015585
 protein coding gene Chr1:164984436-165008799 (-)
WSB/EiJ MGP_WSBEiJ_G0016074
 protein coding gene Chr1:166272787-166301331 (-)



Homology
more
  • Human Ortholog
    FMO2, flavin containing dimethylaniline monoxygenase 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FMO2, flavin containing dimethylaniline monoxygenase 2
  • Synonyms
    FMO1B1
  • Links
    NCBI Gene ID: 2327
    neXtProt AC: NX_Q99518
    UniProt: Q99518

  • Chr Location
    1q24.3; chr1:171185208-171212686 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    22
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1020
  • Tissues
    228
  • cDNA Data
    48
  • Literature Summary
    7
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000040170 Ensembl Gene Model | MGI Sequence Detail 24410 C57BL/6J ±  kb
transcript ENSMUST00000045902 Ensembl | MGI Sequence Detail 4066 Not Applicable  
polypeptide ENSMUSP00000044405 Ensembl | MGI Sequence Detail 535 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 50
    cDNA 49
    Primer pair 1

    Microarray probesets 7
Other
Accession IDs
less
MGI:1923713, MGI:2138560
References
more
  • Summaries
    All 47
    Developmental Gene Expression 7
    Gene Ontology 9
    Phenotypes 11
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:328119 Yoshida Y, et al., Brown adipose tissue dysfunction promotes heart failure via a trimethylamine N-oxide-dependent mechanism. Sci Rep. 2022 Sep 1;12(1):14883
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory