About   Help   FAQ
Ppp1r3d Gene Detail
Summary
  • Symbol
    Ppp1r3d
  • Name
    protein phosphatase 1, regulatory subunit 3D
  • Synonyms
    2610024M03Rik, LOC228966
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917664
    NCBI Gene: 228966
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:178052999-178056256 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 99.91 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    151 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917664
 protein coding gene Chr2:178052999-178056265 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026977
 protein coding gene Chr2:184842196-184845462 (-)
A/J MGP_AJ_G0026943
 protein coding gene Chr2:177228995-177232292 (-)
AKR/J MGP_AKRJ_G0026913
 protein coding gene Chr2:182527405-182530671 (-)
BALB/cJ MGP_BALBcJ_G0026952
 protein coding gene Chr2:177701504-177704771 (-)
C3H/HeJ MGP_C3HHeJ_G0026693
 protein coding gene Chr2:182913420-182916686 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027398
 protein coding gene Chr2:190199992-190207890 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024767
 protein coding gene Chr2:167921552-167924138 (-)
CAST/EiJ MGP_CASTEiJ_G0026152
 protein coding gene Chr2:181139807-181143081 (-)
CBA/J MGP_CBAJ_G0026670
 protein coding gene Chr2:197088212-197091478 (-)
DBA/2J MGP_DBA2J_G0026808
 protein coding gene Chr2:176353618-176356885 (-)
FVB/NJ MGP_FVBNJ_G0026774
 protein coding gene Chr2:174939136-174942402 (-)
LP/J MGP_LPJ_G0026910
 protein coding gene Chr2:184826743-184830009 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026793
 protein coding gene Chr2:199799591-199803917 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027457
 protein coding gene Chr2:182500622-182503888 (-)
PWK/PhJ MGP_PWKPhJ_G0025888
 protein coding gene Chr2:173825994-173829316 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025688
 protein coding gene Chr2:178959802-178963090 (-)
WSB/EiJ MGP_WSBEiJ_G0026224
 protein coding gene Chr2:183486478-183489751 (-)



Homology
more
  • Human Ortholog
    PPP1R3D, protein phosphatase 1 regulatory subunit 3D
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PPP1R3D, protein phosphatase 1 regulatory subunit 3D
  • Synonyms
    PPP1R6
  • Links
    NCBI Gene ID: 5509
    neXtProt AC: NX_O95685
    UniProt: O95685

  • Chr Location
    20q13.33; chr20:59936663-59940305 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 228966 NCBI Gene Model | MGI Sequence Detail 3258 C57BL/6J ±  kb
transcript NM_001085501 RefSeq | MGI Sequence Detail 3272 C57BL/6  
polypeptide NP_001078970 RefSeq | MGI Sequence Detail 279 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR005036 CBM21 (carbohydrate binding type-21) domain
    IPR038175 CBM21 domain superfamily
    IPR050782 Protein phosphatase 1 regulatory subunit 3
    IPR017434 Protein phosphatase 1 regulatory subunit 3B/C/D, metazoa
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 3
Other
Accession IDs
less
MGI:2685205
References
more
  • Summaries
    All 22
    Gene Ontology 2
    Phenotypes 2
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:308348 Israelian L, et al., Ppp1r3d deficiency preferentially inhibits neuronal and cardiac Lafora body formation in a mouse model of the fatal epilepsy Lafora disease. J Neurochem. 2021 Jun;157(6):1897-1910
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory