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Armcx3 Gene Detail
Summary
  • Symbol
    Armcx3
  • Name
    armadillo repeat containing, X-linked 3
  • Synonyms
    1200004E24Rik, Alex3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918953
    NCBI Gene: 71703
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:133657344-133662204 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 56.25 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    127 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918953
 protein coding gene ChrX:133657301-133662206 (+)
129S1/SvImJ MGP_129S1SvImJ_G0036077
 protein coding gene ChrX:131945070-131950432 (+)
A/J MGP_AJ_G0023854
 protein coding gene Chr17:54431196-54432784 (-)
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0023856
 protein coding gene Chr17:54252844-54255279 (-)
C3H/HeJ MGP_C3HHeJ_G0035753
 protein coding gene ChrX:132034149-132038687 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033563
 protein coding gene Chr7:137591880-137600726 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033400
 protein coding gene ChrX:123544570-123549382 (+)
CAST/EiJ MGP_CASTEiJ_G0035041
 protein coding gene ChrX:112903828-112908924 (+)
CBA/J MGP_CBAJ_G0023595
 protein coding gene Chr17:60367322-60369917 (-)
DBA/2J MGP_DBA2J_G0035885
 protein coding gene ChrX:130682107-130688021 (+)
FVB/NJ MGP_FVBNJ_G0035826
 protein coding gene ChrX:130003585-130007102 (+)
LP/J MGP_LPJ_G0035978
 protein coding gene ChrX:132835242-132840546 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035855
 protein coding gene ChrX:147282904-147295216 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036602
 protein coding gene ChrX:131390770-131398918 (+)
PWK/PhJ MGP_PWKPhJ_G0034733
 protein coding gene ChrX:109845475-109850596 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034564
 protein coding gene ChrX:113553783-113561619 (+)
WSB/EiJ MGP_WSBEiJ_G0035179
 protein coding gene ChrX:129758327-129764546 (+)



Homology
more
  • Human Ortholog
    ARMCX3, armadillo repeat containing X-linked 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ARMCX3, armadillo repeat containing X-linked 3
  • Synonyms
    ALEX3, dJ545K15.2, GASP6
  • Links
    NCBI Gene ID: 51566
    neXtProt AC: NX_Q9UH62
    UniProt: Q9UH62

  • Chr Location
    Xq22.1; chrX:101622797-101627843 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    756
  • Tissues
    16
  • cDNA Data
    54
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000049047 Ensembl Gene Model | MGI Sequence Detail 4861 C57BL/6J ±  kb
    transcript ENSMUST00000081834 Ensembl | MGI Sequence Detail 3327 Not Applicable  
    polypeptide ENSMUSP00000080518 Ensembl | MGI Sequence Detail 379 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 56
      cDNA 54
      Primer pair 1
      Other 1

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:2147889
    References
    more
    • Summaries
      All 33
      Developmental Gene Expression 5
      Gene Ontology 4
      Phenotypes 5
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345823 Izquierdo-Villalba I, et al., A mammalian-specific Alex3/Galpha(q) protein complex regulates mitochondrial trafficking, dendritic complexity, and neuronal survival. Sci Signal. 2024 Feb 6;17(822):eabq1007
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory