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Shroom1 Gene Detail
Summary
  • Symbol
    Shroom1
  • Name
    shroom family member 1
  • Synonyms
    1300007L22Rik, Apx, Shrm1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919024
    NCBI Gene: 71774
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:53348032-53358593 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 31.95 cM, cytoband B1.3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    359 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919024
 protein coding gene Chr11:53347904-53358593 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018294
 protein coding gene Chr11:52841316-52851866 (+)
A/J MGP_AJ_G0018263
 protein coding gene Chr11:50858617-50869167 (+)
AKR/J MGP_AKRJ_G0018233
 protein coding gene Chr11:52518832-52531542 (+)
BALB/cJ MGP_BALBcJ_G0018234
 protein coding gene Chr11:51216035-51226581 (+)
C3H/HeJ MGP_C3HHeJ_G0018045
 protein coding gene Chr11:52487198-52497757 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018686
 protein coding gene Chr11:54435950-54446485 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016336
 protein coding gene Chr11:48400579-48411142 (+)
CAST/EiJ MGP_CASTEiJ_G0017610
 protein coding gene Chr11:52532934-52553707 (+)
CBA/J MGP_CBAJ_G0018020
 protein coding gene Chr11:57007487-57018049 (+)
DBA/2J MGP_DBA2J_G0018130
 protein coding gene Chr11:50606884-50617419 (+)
FVB/NJ MGP_FVBNJ_G0018122
 protein coding gene Chr11:50245418-50255962 (+)
LP/J MGP_LPJ_G0018204
 protein coding gene Chr11:53294176-53304725 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018146
 protein coding gene Chr11:58336653-58347197 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018728
 protein coding gene Chr11:52547994-52558541 (+)
PWK/PhJ MGP_PWKPhJ_G0017385
 protein coding gene Chr11:51121494-51141587 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017180
 protein coding gene Chr11:52367582-52378005 (+)
WSB/EiJ MGP_WSBEiJ_G0017657
 protein coding gene Chr11:52185504-52196948 (+)



Homology
more
  • Human Ortholog
    SHROOM1, shroom family member 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SHROOM1, shroom family member 1
  • Synonyms
    APXL2
  • Links
    NCBI Gene ID: 134549
    neXtProt AC: NX_Q2M3G4
    UniProt: Q2M3G4

  • Chr Location
    5q31.1; chr5:132822141-132830659 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    802
  • Tissues
    96
  • cDNA Data
    24
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000018387 Ensembl Gene Model | MGI Sequence Detail 10562 C57BL/6J ±  kb
transcript ENSMUST00000109013 Ensembl | MGI Sequence Detail 3312 Not Applicable  
polypeptide ENSMUSP00000104641 Ensembl | MGI Sequence Detail 823 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 27
    Genomic 1
    cDNA 24
    Primer pair 1
    Other 1

    Microarray probesets 2
References
more
  • Summaries
    All 32
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 8
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:325730 Ahuja N, et al., Endothelial Cyp26b1 restrains murine heart valve growth during development. Dev Biol. 2022 Jun;486:81-95
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory