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Adipor1 Gene Detail
Summary
  • Symbol
    Adipor1
  • Name
    adiponectin receptor 1
  • Synonyms
    2810031L11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919924
    NCBI Gene: 72674
  • Alliance
    gene page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:134343116-134361089 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 58.22 cM, cytoband E4
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    493 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919924
 protein coding gene Chr1:134343116-134361089 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016507
 protein coding gene Chr1:138073837-138092890 (+)
A/J MGP_AJ_G0016490
 protein coding gene Chr1:132873460-132891419 (+)
AKR/J MGP_AKRJ_G0016455
 protein coding gene Chr1:136840207-136858109 (+)
BALB/cJ MGP_BALBcJ_G0016450
 protein coding gene Chr1:133208643-133227931 (+)
C3H/HeJ MGP_C3HHeJ_G0016276
 protein coding gene Chr1:136938710-136956652 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016911
 protein coding gene Chr1:143107652-143125589 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014622
 protein coding gene Chr1:126010888-126028846 (+)
CAST/EiJ MGP_CASTEiJ_G0015856
 protein coding gene Chr1:135993629-136011652 (+)
CBA/J MGP_CBAJ_G0016249
 protein coding gene Chr1:148064637-148082675 (+)
DBA/2J MGP_DBA2J_G0016355
 protein coding gene Chr1:131889138-131907095 (+)
FVB/NJ MGP_FVBNJ_G0016354
 protein coding gene Chr1:130514252-130532206 (+)
LP/J MGP_LPJ_G0016426
 protein coding gene Chr1:139352369-139370358 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016379
 protein coding gene Chr1:153754271-153775409 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016947
 protein coding gene Chr1:136571559-136589502 (+)
PWK/PhJ MGP_PWKPhJ_G0015642
 protein coding gene Chr1:130912586-130930960 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015429
 protein coding gene Chr1:135547910-135564915 (+)
WSB/EiJ MGP_WSBEiJ_G0015919
 protein coding gene Chr1:136604074-136622025 (+)



Homology
more
  • Human Ortholog
    ADIPOR1, adiponectin receptor 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ADIPOR1, adiponectin receptor 1
  • Synonyms
    ACDCR1, CGI-45, CGI45, PAQR1, TESBP1A
  • Links
    NCBI Gene ID: 51094
    neXtProt AC: NX_Q96A54
    UniProt: Q96A54

  • Chr Location
    1q32.1; chr1:202940825-202958572 (-)  GRCh38
Human Diseases
more
  • Diseases
    3 with human ADIPOR1 associations

Human Disease Mouse Models
      
IDs
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    48 phenotypes from 5 alleles in 8 genetic backgrounds
    10 phenotypes from multigenic genotypes
    50 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a targeted allele exhibit abnormal homeostasis, adipose tissue morphology and adaptive thermogenesis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    47
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    978
  • Tissues
    141
  • cDNA Data
    229
  • Literature Summary
    13
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 72674 NCBI Gene Model | MGI Sequence Detail 17974 C57BL/6J ±  kb
    transcript NM_001306069 RefSeq | MGI Sequence Detail 3255 C57BL/6  
    polypeptide Q91VH1 UniProt | EBI | MGI Sequence Detail 375 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 235
      cDNA 230
      Primer pair 5

      Microarray probesets 5
    References
    more
    • Summaries
      All 115
      Developmental Gene Expression 13
      Gene Ontology 11
      Phenotypes 50
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:349326 Lewandowski D, et al., Restoring retinal polyunsaturated fatty acid balance and retina function by targeting ceramide in AdipoR1-deficient mice. J Biol Chem. 2024 Apr 16;300(5):107291
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/05/2024
    MGI 6.24     		The Jackson Laboratory