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Asz1 Gene Detail
Summary
  • Symbol
    Asz1
  • Name
    ankyrin repeat, SAM and basic leucine zipper domain containing 1
  • Synonyms
    4933400N19Rik, Gasz, ORF3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921318
    NCBI Gene: 74068
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:18050963-18109060 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 8.09 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1143 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921318
 protein coding gene Chr6:18050963-18109060 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030474
 protein coding gene Chr6:15335487-15393028 (-)
A/J MGP_AJ_G0030447
 protein coding gene Chr6:14712218-14766061 (-)
AKR/J MGP_AKRJ_G0030374
 protein coding gene Chr6:15216180-15281674 (-)
BALB/cJ MGP_BALBcJ_G0030456
 protein coding gene Chr6:14801928-14857890 (-)
C3H/HeJ MGP_C3HHeJ_G0030170
 protein coding gene Chr6:15094747-15153303 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030911
 protein coding gene Chr6:15810975-15869401 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028122
 protein coding gene Chr6:13653422-13709950 (-)
CAST/EiJ MGP_CASTEiJ_G0029572
 protein coding gene Chr6:14999690-15060693 (-)
CBA/J MGP_CBAJ_G0030148
 protein coding gene Chr6:16324035-16389197 (-)
DBA/2J MGP_DBA2J_G0030292
 protein coding gene Chr6:14640087-14691553 (-)
FVB/NJ MGP_FVBNJ_G0030246
 protein coding gene Chr6:14469293-14524963 (-)
LP/J MGP_LPJ_G0030379
 protein coding gene Chr6:15444001-15499198 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030282
 protein coding gene Chr6:17478848-17536808 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030941
 protein coding gene Chr6:15102458-15168538 (-)
PWK/PhJ MGP_PWKPhJ_G0029286
 protein coding gene Chr6:14299008-14354058 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029122
 protein coding gene Chr6:14991638-15042321 (-)
WSB/EiJ MGP_WSBEiJ_G0029648
 protein coding gene Chr6:15039717-15098551 (-)



Homology
more
  • Human Ortholog
    ASZ1, ankyrin repeat, SAM and basic leucine zipper domain containing 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ASZ1, ankyrin repeat, SAM and basic leucine zipper domain containing 1
  • Synonyms
    ALP1, ANKL1, C7orf7, CT1.19, GASZ, Orf3
  • Links
    NCBI Gene ID: 136991
    neXtProt AC: NX_Q8WWH4
    UniProt: Q8WWH4

  • Chr Location
    7q31.2; chr7:117363222-117428123 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    1 images
    3 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null male mice are sterile resulting from a block in spermatid development
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    739
  • Tissues
    32
  • cDNA Data
    12
  • Literature Summary
    8
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 74068 NCBI Gene Model | MGI Sequence Detail 58098 C57BL/6J ±  kb
    transcript NM_023729 RefSeq | MGI Sequence Detail 1740 Not Specified  
    polypeptide Q8VD46 UniProt | EBI | MGI Sequence Detail 475 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 13
      cDNA 12
      Primer pair 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:1353469
    References
    more
    • Summaries
      All 30
      Developmental Gene Expression 8
      Gene Ontology 4
      Phenotypes 3
    • Earliest
      J:60184 Ellsworth RE, et al., Comparative genomic sequence analysis of the human and mouse cystic fibrosis transmembrane conductance regulator genes. Proc Natl Acad Sci U S A. 2000 Feb 1;97(3):1172-7
    • Latest
      J:271018 Auclair G, et al., EHMT2 directs DNA methylation for efficient gene silencing in mouse embryos. Genome Res. 2016 Feb;26(2):192-202
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory