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4931414P19Rik Gene Detail
Summary
  • Symbol
    4931414P19Rik
  • Name
    RIKEN cDNA 4931414P19 gene
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921609
    NCBI Gene: 74359
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:54821120-54843450 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 27.85 cM, cytoband C1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    605 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921609
 protein coding gene Chr14:54821119-54843450 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021315
 protein coding gene Chr14:48545106-48569055 (-)
A/J MGP_AJ_G0021274
 protein coding gene Chr14:47596110-47618090 (-)
AKR/J MGP_AKRJ_G0021250
 protein coding gene Chr14:49309081-49336002 (-)
BALB/cJ MGP_BALBcJ_G0021278
 protein coding gene Chr14:47570348-47593448 (-)
C3H/HeJ MGP_C3HHeJ_G0021058
 protein coding gene Chr14:49009624-49034897 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021717
 protein coding gene Chr14:51010520-51032585 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019261
 protein coding gene Chr14:46010112-46033084 (-)
CAST/EiJ MGP_CASTEiJ_G0020577
 protein coding gene Chr14:45248192-45271811 (-)
CBA/J MGP_CBAJ_G0021025
 protein coding gene Chr14:52520210-52544757 (-)
DBA/2J MGP_DBA2J_G0021146
 protein coding gene Chr14:47336895-47358729 (-)
FVB/NJ MGP_FVBNJ_G0021128
 protein coding gene Chr14:46789617-46811896 (-)
LP/J MGP_LPJ_G0021220
 protein coding gene Chr14:49549440-49572984 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021152
 protein coding gene Chr14:51941536-51966288 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021743
 protein coding gene Chr14:48502521-48527838 (-)
PWK/PhJ MGP_PWKPhJ_G0020323
 protein coding gene Chr14:43865148-43888108 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020151
 protein coding gene Chr14:44485346-44511157 (-)
WSB/EiJ MGP_WSBEiJ_G0020630
 protein coding gene Chr14:48794173-48816859 (-)



Homology
more
  • Human Ortholog
    C14orf93, chromosome 14 open reading frame 93
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    C14orf93, chromosome 14 open reading frame 93
  • Synonyms
    RTFC
  • Links
    NCBI Gene ID: 60686
    neXtProt AC: NX_Q9H972
    UniProt: Q9H972

  • Chr Location
    14q11.2; chr14:22985894-23010166 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit mild hypothyrodism in female, but not male, mice.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    18
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000022179 Ensembl Gene Model | MGI Sequence Detail 22331 C57BL/6J ±  kb
    transcript ENSMUST00000022786 Ensembl | MGI Sequence Detail 2670 Not Applicable  
    polypeptide ENSMUSP00000022786 Ensembl | MGI Sequence Detail 541 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 18
      cDNA 18

      Microarray probesets 3
    References
    more
    • Summaries
      All 28
      Gene Ontology 2
      Phenotypes 7
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:341275 Mestres I, et al., 4931414P19Rik, a microglia chemoattractant secreted by neural progenitors, modulates neuronal migration during corticogenesis. Development. 2023 May 1;150(9)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory