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Scpep1 Gene Detail
Summary
  • Symbol
    Scpep1
  • Name
    serine carboxypeptidase 1
  • Synonyms
    2410018F01Rik, 4833411K15Rik, Risc
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921867
    NCBI Gene: 74617
  • Alliance
    gene page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:88814846-88846268 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 54.34 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    734 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921867
 protein coding gene Chr11:88814846-88846291 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018926
 protein coding gene Chr11:90677367-90711789 (-)
A/J MGP_AJ_G0018894
 protein coding gene Chr11:87143674-87176226 (-)
AKR/J MGP_AKRJ_G0018864
 protein coding gene Chr11:89805479-89836137 (-)
BALB/cJ MGP_BALBcJ_G0018867
 protein coding gene Chr11:87559518-87593199 (-)
C3H/HeJ MGP_C3HHeJ_G0018681
 protein coding gene Chr11:89826889-89858645 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019319
 protein coding gene Chr11:93435555-93470101 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016950
 protein coding gene Chr11:84165783-84196810 (-)
CAST/EiJ MGP_CASTEiJ_G0018236
 protein coding gene Chr11:90536070-90575059 (-)
CBA/J MGP_CBAJ_G0018652
 protein coding gene Chr11:97427797-97463906 (-)
DBA/2J MGP_DBA2J_G0018760
 protein coding gene Chr11:86696723-86728802 (-)
FVB/NJ MGP_FVBNJ_G0018749
 protein coding gene Chr11:86201154-86234938 (-)
LP/J MGP_LPJ_G0018830
 protein coding gene Chr11:91186489-91223132 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018776
 protein coding gene Chr11:97350298-97382366 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019359
 protein coding gene Chr11:90019207-90050705 (-)
PWK/PhJ MGP_PWKPhJ_G0018006
 protein coding gene Chr11:87548093-87584123 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017797
 protein coding gene Chr11:89593805-89635550 (-)
WSB/EiJ MGP_WSBEiJ_G0018285
 protein coding gene Chr11:89908277-89940188 (-)



Homology
more
  • Human Ortholog
    SCPEP1, serine carboxypeptidase 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SCPEP1, serine carboxypeptidase 1
  • Synonyms
    HSCP1, RISC
  • Links
    NCBI Gene ID: 59342
    neXtProt AC: NX_Q9HB40
    UniProt: Q9HB40

  • Chr Location
    17q22; chr17:56978129-57006768 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 2 alleles in 2 genetic backgrounds
    26 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    299
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Gene trapped
    290
  • Targeted
    6
  • Genomic Mutations
    4 involving Scpep1
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    62 strains or lines available
Mice homozygous for a gene trapped allele exhibit no abnormal phenotype. Mice homozygous for a knock-out allele exhibit abnormal blood vessel healing.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    910
  • Tissues
    128
  • cDNA Data
    114
  • Literature Summary
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 74617 NCBI Gene Model | MGI Sequence Detail 31423 C57BL/6J ±  kb
transcript NM_029023 RefSeq | MGI Sequence Detail 2087 C57BL/6  
polypeptide Q920A5 UniProt | EBI | MGI Sequence Detail 452 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 116
    cDNA 115
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:1916970, MGI:2144331
References
more
  • Summaries
    All 57
    Developmental Gene Expression 6
    Diseases 1
    Gene Ontology 4
    Phenotypes 26
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory