About   Help   FAQ
Kif27 Gene Detail
Summary
  • Symbol
    Kif27
  • Name
    kinesin family member 27
  • Synonyms
    4930517I18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922300
    NCBI Gene: 75050
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:58435316-58506936 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 30.99 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2081 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922300
 protein coding gene Chr13:58432541-58512559 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020631
 protein coding gene Chr13:57920343-57993807 (-)
A/J MGP_AJ_G0020585
 protein coding gene Chr13:55770517-55838116 (-)
AKR/J MGP_AKRJ_G0020563
 protein coding gene Chr13:57434301-57502941 (-)
BALB/cJ MGP_BALBcJ_G0020581
 protein coding gene Chr13:56020446-56092187 (-)
C3H/HeJ MGP_C3HHeJ_G0020380
 protein coding gene Chr13:57240491-57304354 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021015
 protein coding gene Chr13:59700972-59774783 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018597
 protein coding gene Chr13:53669639-53736739 (-)
CAST/EiJ MGP_CASTEiJ_G0019894
 protein coding gene Chr13:57371528-57445992 (-)
CBA/J MGP_CBAJ_G0020340
 protein coding gene Chr13:61949068-62017504 (-)
DBA/2J MGP_DBA2J_G0020463
 protein coding gene Chr13:55311127-55388280 (-)
FVB/NJ MGP_FVBNJ_G0020442
 protein coding gene Chr13:54799341-54863935 (-)
LP/J MGP_LPJ_G0020539
 protein coding gene Chr13:58198094-58270171 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020471
 protein coding gene Chr13:61316254-61387924 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021058
 protein coding gene Chr13:57032659-57105557 (-)
PWK/PhJ MGP_PWKPhJ_G0019650
 protein coding gene Chr13:55325985-55397806 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019477
 protein coding gene Chr13:55946322-56017053 (-)
WSB/EiJ MGP_WSBEiJ_G0019956
 protein coding gene Chr13:57475712-57545357 (-)



Homology
more
  • Human Ortholog
    KIF27, kinesin family member 27
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KIF27, kinesin family member 27
  • Links
    NCBI Gene ID: 55582
    neXtProt AC: NX_Q86VH2
    UniProt: Q86VH2

  • Chr Location
    9q21.32; chr9:83834099-83921465 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with Kif27 mouse models

Human Disease Mouse Models
      
IDs
 View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous mice are small and die by 8 weeks and exhibit hydrocephalus, rhinitis and otitis media.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    758
  • Tissues
    18
  • cDNA Data
    8
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000060176 Ensembl Gene Model | MGI Sequence Detail 71621 C57BL/6J ±  kb
    transcript ENSMUST00000225388 Ensembl | MGI Sequence Detail 5121 Not Applicable  
    polypeptide ENSMUSP00000153598 Ensembl | MGI Sequence Detail 1394 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 11
      cDNA 11

      Microarray probesets 2
    References
    more
    • Summaries
      All 32
      Developmental Gene Expression 2
      Diseases 1
      Gene Ontology 6
      Phenotypes 9
    • Earliest
      J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
    • Latest
      J:185566 Vogel P, et al., Congenital hydrocephalus in genetically engineered mice. Vet Pathol. 2012 Jan;49(1):166-81
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory