About   Help   FAQ
Rsph9 Gene Detail
Summary
  • Symbol
    Rsph9
  • Name
    radial spoke head 9 homolog (Chlamydomonas)
  • Synonyms
    1700027N10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922814
    NCBI Gene: 75564
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:46432961-46455142 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 22.87 cM, cytoband C
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    605 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922814
 protein coding gene Chr17:46432961-46455171 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023802
 protein coding gene Chr17:47164545-47189145 (-)
A/J MGP_AJ_G0023760
 protein coding gene Chr17:46030726-46052823 (-)
AKR/J MGP_AKRJ_G0023731
 protein coding gene Chr17:46361718-46385118 (-)
BALB/cJ MGP_BALBcJ_G0023764
 protein coding gene Chr17:45918898-45941281 (-)
C3H/HeJ MGP_C3HHeJ_G0023528
 protein coding gene Chr17:47092156-47114066 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024207
 protein coding gene Chr17:49211718-49234057 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021657
 protein coding gene Chr17:42831955-42854058 (-)
CAST/EiJ MGP_CASTEiJ_G0023009
 protein coding gene Chr17:47213957-47237324 (-)
CBA/J MGP_CBAJ_G0023504
 protein coding gene Chr17:50959113-50981774 (-)
DBA/2J MGP_DBA2J_G0023630
 protein coding gene Chr17:44820213-44842322 (-)
FVB/NJ MGP_FVBNJ_G0023597
 protein coding gene Chr17:44423868-44446470 (-)
LP/J MGP_LPJ_G0023711
 protein coding gene Chr17:47824634-47852775 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023626
 protein coding gene Chr17:50518101-50541102 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024252
 protein coding gene Chr17:46714083-46736142 (-)
PWK/PhJ MGP_PWKPhJ_G0022754
 protein coding gene Chr17:44133937-44156677 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022569
 protein coding gene Chr17:43612428-43634760 (-)
WSB/EiJ MGP_WSBEiJ_G0023074
 protein coding gene Chr17:47267245-47289451 (-)



Homology
more
  • Human Ortholog
    RSPH9, radial spoke head component 9
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RSPH9, radial spoke head component 9
  • Synonyms
    C6orf206, CILD12, MRPS18AL1
  • Links
    NCBI Gene ID: 221421
    neXtProt AC: NX_Q9H1X1
    UniProt: Q9H1X1

  • Chr Location
    6p21.1; chr6:43645036-43672600 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human RSPH9 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    34 phenotypes from 2 alleles in 2 genetic backgrounds
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit postnatal lethality, hydrocephaly, ventriculomegaly, abnormal brain ependyma motile cilium morphology and physiology, reduced cerebrospinal fluid flow, astrogliosis, microgliosis, cerebrovascular and myelination abnormalities, and severe sinusitis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    29
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    760
  • Tissues
    9
  • cDNA Data
    19
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000023966 Ensembl Gene Model | MGI Sequence Detail 22182 C57BL/6J ±  kb
    transcript ENSMUST00000024762 Ensembl | MGI Sequence Detail 966 Not Applicable  
    polypeptide ENSMUSP00000024762 Ensembl | MGI Sequence Detail 276 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 20
      cDNA 19
      Primer pair 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 45
      Developmental Gene Expression 4
      Gene Ontology 10
      Phenotypes 12
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory