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Spaca3 Gene Detail
Summary
  • Symbol
    Spaca3
  • Name
    sperm acrosome associated 3
  • Synonyms
    1700025M08Rik, ALLP17, SLLP1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922872
    NCBI Gene: 75622
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:80749191-80758640 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 48.40 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    417 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922872
 protein coding gene Chr11:80749189-80758640 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018817
 protein coding gene Chr11:82042770-82052708 (+)
A/J MGP_AJ_G0018784
 protein coding gene Chr11:78896404-78906706 (+)
AKR/J MGP_AKRJ_G0018754
 protein coding gene Chr11:81242555-81251538 (+)
BALB/cJ MGP_BALBcJ_G0018757
 protein coding gene Chr11:79291737-79301263 (+)
C3H/HeJ MGP_C3HHeJ_G0018571
 protein coding gene Chr11:81321521-81331324 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019209
 protein coding gene Chr11:84543543-84557007 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016843
 protein coding gene Chr11:75820242-75829272 (+)
CAST/EiJ MGP_CASTEiJ_G0018126
 protein coding gene Chr11:81806930-81819248 (+)
CBA/J MGP_CBAJ_G0018542
 protein coding gene Chr11:88259411-88276806 (+)
DBA/2J MGP_DBA2J_G0018650
 protein coding gene Chr11:78449583-78460478 (+)
FVB/NJ MGP_FVBNJ_G0018639
 protein coding gene Chr11:78012347-78021678 (+)
LP/J MGP_LPJ_G0018720
 protein coding gene Chr11:82566661-82576914 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018666
 protein coding gene Chr11:88515788-88528019 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019249
 protein coding gene Chr11:81534201-81544667 (+)
PWK/PhJ MGP_PWKPhJ_G0017896
 protein coding gene Chr11:79267373-79277992 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017687
 protein coding gene Chr11:81127787-81139404 (+)
WSB/EiJ MGP_WSBEiJ_G0018178
 protein coding gene Chr11:81365127-81380493 (+)



Homology
more
  • Human Ortholog
    SPACA3, sperm acrosome associated 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SPACA3, sperm acrosome associated 3
  • Synonyms
    ALLP17, CT54, LYC3, LYZC, LYZL3, SLLP1
  • Links
    NCBI Gene ID: 124912
    neXtProt AC: NX_Q8IXA5
    UniProt: Q8IXA5

  • Chr Location
    17q11.2
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Targeted
    2
  • Genomic Mutations
    2 involving Spaca3
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    12 strains or lines available
Male mice homozygous for a mutation are viable and show normal fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    13
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000053184 Ensembl Gene Model | MGI Sequence Detail 9450 C57BL/6J ±  kb
transcript ENSMUST00000103222 Ensembl | MGI Sequence Detail 831 Not Applicable  
polypeptide ENSMUSP00000099511 Ensembl | MGI Sequence Detail 163 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 13

    Microarray probesets 5
References
more
  • Summaries
    All 36
    Developmental Gene Expression 1
    Gene Ontology 8
    Phenotypes 10
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:234235 Miyata H, et al., Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice. Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):7704-10
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory