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Psmg2 Gene Detail
Summary
  • Symbol
    Psmg2
  • Name
    proteasome (prosome, macropain) assembly chaperone 2
  • Synonyms
    1700017I17Rik, Clast3, Tnfsf5ip1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922901
    NCBI Gene: 107047
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:67774669-67787232 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 40.05 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    549 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922901
 protein coding gene Chr18:67774657-67787251 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024528
 protein coding gene Chr18:67949131-67961678 (+)
A/J MGP_AJ_G0024495
 protein coding gene Chr18:64979953-64992674 (+)
AKR/J MGP_AKRJ_G0024466
 protein coding gene Chr18:66886805-66899351 (+)
BALB/cJ MGP_BALBcJ_G0024495
 protein coding gene Chr18:65146667-65159205 (+)
C3H/HeJ MGP_C3HHeJ_G0024263
 protein coding gene Chr18:67040533-67053090 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024941
 protein coding gene Chr18:69728347-69740903 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022372
 protein coding gene Chr18:64356348-64368902 (+)
CAST/EiJ MGP_CASTEiJ_G0023735
 protein coding gene Chr18:67040954-67055453 (+)
CBA/J MGP_CBAJ_G0024232
 protein coding gene Chr18:72143374-72155926 (+)
DBA/2J MGP_DBA2J_G0024362
 protein coding gene Chr18:64628770-64641324 (+)
FVB/NJ MGP_FVBNJ_G0024328
 protein coding gene Chr18:64000335-64012999 (+)
LP/J MGP_LPJ_G0024446
 protein coding gene Chr18:67809662-67823755 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024358
 protein coding gene Chr18:73412223-73426266 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024989
 protein coding gene Chr18:67050835-67064852 (+)
PWK/PhJ MGP_PWKPhJ_G0023480
 protein coding gene Chr18:64914562-64927503 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023284
 protein coding gene Chr18:67218276-67231040 (+)
WSB/EiJ MGP_WSBEiJ_G0023799
 protein coding gene Chr18:66960225-66975563 (+)



Homology
more
  • Human Ortholog
    PSMG2, proteasome assembly chaperone 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PSMG2, proteasome assembly chaperone 2
  • Synonyms
    CLAST3, HCCA3, HsT1707, MDS003, PAC2, PRAAS4, TNFSF5IP1
  • Links
    NCBI Gene ID: 56984
    neXtProt AC: NX_Q969U7
    UniProt: Q969U7

  • Chr Location
    18p11.21; chr18:12658043-12728945 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human PSMG2 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    76
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024537 Ensembl Gene Model | MGI Sequence Detail 12564 C57BL/6J ±  kb
transcript ENSMUST00000025418 Ensembl | MGI Sequence Detail 1059 Not Applicable  
polypeptide ENSMUSP00000025418 Ensembl | MGI Sequence Detail 264 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000013398 proteasome assembly chaperone 2
    (term hierarchy)
  • InterPro Domains
    IPR019151 Proteasome assembly chaperone 2
    IPR016562 Proteasome assembly chaperone 2, eukaryotic
    IPR038389 Proteasome assembly chaperone 2 superfamily
  • GlyGen
    Q9EST4 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 76
    cDNA 76

    Microarray probesets 4
Other
Accession IDs
less
MGI:2147369
References
more
  • Summaries
    All 34
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:184521 Koss M, et al., Congenital Asplenia in Mice and Humans with Mutations in a Pbx/Nkx2-5/p15 Module. Dev Cell. 2012 May 15;22(5):913-26
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory