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Clec4g Gene Detail
Summary
  • Symbol
    Clec4g
  • Name
    C-type lectin domain family 4, member g
  • Synonyms
    4930572L20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923113
    NCBI Gene: 75863
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:3757064-3770651 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 1.92 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    426 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923113
 protein coding gene Chr8:3757064-3770695 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033317
 protein coding gene Chr8:659075-672658 (-)
A/J MGP_AJ_G0033300
 protein coding gene Chr8:623335-637657 (-)
AKR/J MGP_AKRJ_G0033231
 protein coding gene Chr8:654349-667936 (-)
BALB/cJ MGP_BALBcJ_G0033300
 protein coding gene Chr8:649564-663149 (-)
C3H/HeJ MGP_C3HHeJ_G0033014
 protein coding gene Chr8:669600-683214 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033810
 protein coding gene Chr8:702935-716691 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030783
 protein coding gene Chr8:575822-590605 (-)
CAST/EiJ MGP_CASTEiJ_G0032337
 protein coding gene Chr8:664032-679839 (-)
CBA/J MGP_CBAJ_G0032987
 protein coding gene Chr8:726537-740124 (-)
DBA/2J MGP_DBA2J_G0033141
 protein coding gene Chr8:594347-607932 (-)
FVB/NJ MGP_FVBNJ_G0033088
 protein coding gene Chr8:642108-655696 (-)
LP/J MGP_LPJ_G0033233
 protein coding gene Chr8:636628-650213 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033123
 protein coding gene Chr8:694396-707983 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033828
 protein coding gene Chr8:648392-661984 (-)
PWK/PhJ MGP_PWKPhJ_G0032047
 protein coding gene Chr8:623743-637316 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031891
 protein coding gene Chr8:645921-661694 (-)
WSB/EiJ MGP_WSBEiJ_G0032450
 protein coding gene Chr8:644133-657751 (-)



Homology
more
  • Human Ortholog
    CLEC4G, C-type lectin domain family 4 member G
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CLEC4G, C-type lectin domain family 4 member G
  • Synonyms
    DTTR431, LP2698, LSECtin, UNQ431
  • Links
    NCBI Gene ID: 339390
    neXtProt AC: NX_Q6UXB4
    UniProt: Q6UXB4

  • Chr Location
    19p13.2; chr19:7728957-7733906 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotypes from 2 alleles in 2 genetic backgrounds
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit increased intrahepatic T cell immunity, enhanced immune-mediated liver injury during Con A-induced experimental acute hepatitis, and accelerated CTL-dependent adenovirus clearance.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    30
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    8
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000074491 Ensembl Gene Model | MGI Sequence Detail 13588 C57BL/6J ±  kb
    transcript ENSMUST00000062037 Ensembl | MGI Sequence Detail 1242 Not Applicable  
    polypeptide ENSMUSP00000059574 Ensembl | MGI Sequence Detail 294 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 10
      Genomic 1
      cDNA 9

      Microarray probesets 5
    References
    more
    • Summaries
      All 38
      Gene Ontology 6
      Phenotypes 14
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:266523 Yang Z, et al., C-type lectin receptor LSECtin-mediated apoptotic cell clearance by macrophages directs intestinal repair in experimental colitis. Proc Natl Acad Sci U S A. 2018 Oct 23;115(43):11054-11059
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory