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Coa5 Gene Detail
Summary
  • Symbol
    Coa5
  • Name
    cytochrome C oxidase assembly factor 5
  • Synonyms
    1700001A24Rik, 6330578E17Rik, Pet191
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923428
    NCBI Gene: 76178
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:37456166-37469184 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 15.46 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    400 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923428
 protein coding gene Chr1:37456165-37469184 (-)
129S1/SvImJ MGP_129S1SvImJ_G0015937
 protein coding gene Chr1:36029916-36050325 (-)
A/J MGP_AJ_G0015921
 protein coding gene Chr1:35044625-35058737 (-)
AKR/J MGP_AKRJ_G0015876
 protein coding gene Chr1:35533016-35547580 (-)
BALB/cJ MGP_BALBcJ_G0015875
 protein coding gene Chr1:34717683-34731076 (-)
C3H/HeJ MGP_C3HHeJ_G0015708
 protein coding gene Chr1:35760381-35773560 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016328
 protein coding gene Chr1:37619853-37632825 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014050
 protein coding gene Chr1:32061820-32074835 (-)
CAST/EiJ MGP_CASTEiJ_G0015289
 protein coding gene Chr1:35617057-35630514 (-)
CBA/J MGP_CBAJ_G0015680
 protein coding gene Chr1:38640143-38653097 (-)
DBA/2J MGP_DBA2J_G0015781
 protein coding gene Chr1:34368173-34381211 (-)
FVB/NJ MGP_FVBNJ_G0015783
 protein coding gene Chr1:33902280-33915270 (-)
LP/J MGP_LPJ_G0015851
 protein coding gene Chr1:36379755-36392739 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0015803
 protein coding gene Chr1:40835450-40849192 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016375
 protein coding gene Chr1:35595358-35609764 (-)
PWK/PhJ MGP_PWKPhJ_G0015072
 protein coding gene Chr1:34131954-34145307 (-)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0015351
 protein coding gene Chr1:35546433-35560577 (-)



Homology
more
  • Human Ortholog
    COA5, cytochrome c oxidase assembly factor 5
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    COA5, cytochrome c oxidase assembly factor 5
  • Synonyms
    6330578E17Rik, C2orf64, CEMCOX3, MC4DN9, Pet191
  • Links
    NCBI Gene ID: 493753
    neXtProt AC: NX_Q86WW8
    UniProt: Q86WW8

  • Chr Location
    chr2:98599314-98608515 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human COA5 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    797
  • Tissues
    18
  • cDNA Data
    121
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 76178 NCBI Gene Model | MGI Sequence Detail 13019 C57BL/6J ±  kb
    transcript NM_198006 RefSeq | MGI Sequence Detail 3862 C57BL/6  
    polypeptide Q99M07 UniProt | EBI | MGI Sequence Detail 74 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 121
      cDNA 121

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:1922068
    References
    more
    • Summaries
      All 37
      Developmental Gene Expression 2
      Gene Ontology 3
      Phenotypes 12
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/05/2024
    MGI 6.24     		The Jackson Laboratory