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Trim12a Gene Detail
Summary
  • Symbol
    Trim12a
  • Name
    tripartite motif-containing 12A
  • Synonyms
    2310043C01Rik, Trim12
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923931
    NCBI Gene: 76681
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:103949101-103964673 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 55.69 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    506 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923931
 protein coding gene Chr7:103949100-103964765 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032709
 protein coding gene Chr7:107470344-107504617 (-)
A/J MGP_AJ_G0032684
 protein coding gene Chr7:104660406-104689785 (-)
AKR/J MGP_AKRJ_G0032617
 protein coding gene Chr7:107184586-107313282 (-)
BALB/cJ MGP_BALBcJ_G0032694
 protein coding gene Chr7:104393033-104422343 (-)
C3H/HeJ MGP_C3HHeJ_G0032405
 protein coding gene Chr7:107541811-107569696 (-)
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0031734
 protein coding gene Chr7:99199422-99239893 (-)
CBA/J MGP_CBAJ_G0032373
 protein coding gene Chr7:115448984-115480015 (-)
DBA/2J MGP_DBA2J_G0032527
 protein coding gene Chr7:102995630-103023957 (-)
FVB/NJ MGP_FVBNJ_G0032480
 protein coding gene Chr7:102703079-102734006 (-)
LP/J MGP_LPJ_G0032620
 protein coding gene Chr7:108803887-108833422 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032514
 protein coding gene Chr7:116834490-116960146 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033217
 protein coding gene Chr7:106388461-106501431 (-)
PWK/PhJ MGP_PWKPhJ_G0031448
 protein coding gene Chr7:95984916-96025579 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031293
 protein coding gene Chr7:93612219-93644800 (-)
WSB/EiJ MGP_WSBEiJ_G0031849
 protein coding gene Chr7:107130429-107163612 (-)



Homology
more
  • Human Ortholog
    TRIM5, tripartite motif containing 5
  • Vertebrate Orthologs
    9
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TRIM5, tripartite motif containing 5
  • Synonyms
    RNF88, TRIM5alpha
  • Links
    NCBI Gene ID: 85363
    neXtProt AC: NX_Q9C035
    UniProt: Q9C035

  • Chr Location
    11p15.4; chr11:5588635-5938619 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    33
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    774
  • Tissues
    47
  • cDNA Data
    8
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000066258 Ensembl Gene Model | MGI Sequence Detail 15573 C57BL/6J ±  kb
transcript ENSMUST00000106839 Ensembl | MGI Sequence Detail 1486 Not Applicable  
polypeptide ENSMUSP00000102452 Ensembl | MGI Sequence Detail 297 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    Genomic 2
    cDNA 8

    Microarray probesets 3
References
more
  • Summaries
    All 39
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 10
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:349812 Schafer A, et al., Mapping of susceptibility loci for Ebola virus pathogenesis in mice. Cell Rep. 2024 May 28;43(5):114127
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory