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Bcl9 Gene Detail
Summary
  • Symbol
    Bcl9
  • Name
    B cell CLL/lymphoma 9
  • Synonyms
    2610202E01Rik, 8030475K17Rik, A330041G23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924828
    NCBI Gene: 77578
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:97110978-97205233 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 42.04 cM, cytoband F2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1928 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924828
 protein coding gene Chr3:97110974-97205718 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027639
 protein coding gene Chr3:98123464-98218106 (-)
A/J MGP_AJ_G0027601
 protein coding gene Chr3:94994636-95086789 (-)
AKR/J MGP_AKRJ_G0027568
 protein coding gene Chr3:97259592-97351318 (-)
BALB/cJ MGP_BALBcJ_G0027611
 protein coding gene Chr3:94803772-94894692 (-)
C3H/HeJ MGP_C3HHeJ_G0027343
 protein coding gene Chr3:97542226-97638830 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028057
 protein coding gene Chr3:101744394-101841184 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025398
 protein coding gene Chr3:91225424-91312899 (-)
CAST/EiJ MGP_CASTEiJ_G0026798
 protein coding gene Chr3:96801594-96895586 (-)
CBA/J MGP_CBAJ_G0027318
 protein coding gene Chr3:105398439-105489791 (-)
DBA/2J MGP_DBA2J_G0027461
 protein coding gene Chr3:94298997-94388940 (-)
FVB/NJ MGP_FVBNJ_G0027430
 protein coding gene Chr3:92315088-92402177 (-)
LP/J MGP_LPJ_G0027566
 protein coding gene Chr3:99397548-99490664 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027456
 protein coding gene Chr3:111485942-111579950 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028111
 protein coding gene Chr3:96855073-96949794 (-)
PWK/PhJ MGP_PWKPhJ_G0026523
 protein coding gene Chr3:94149573-94239677 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026345
 protein coding gene Chr3:95127445-95217264 (-)
WSB/EiJ MGP_WSBEiJ_G0026876
 protein coding gene Chr3:97304139-97395861 (-)



Homology
more
  • Human Ortholog
    BCL9, BCL9 transcription coactivator
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    BCL9, BCL9 transcription coactivator
  • Synonyms
    LGS
  • Links
    NCBI Gene ID: 607
    neXtProt AC: NX_O00512
    UniProt: O00512

  • Chr Location
    1q21.2; chr1:147541501-147626216 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    3 phenotypes from multigenic genotypes
    23 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice carrying homozygous floxed Bcl9 and Bcl9l alleles, inactivated in muscle cells, exhibit impaired muscle regeneration due to increased apoptosis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    29
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    770
  • Tissues
    46
  • cDNA Data
    11
  • Literature Summary
    9
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000038256 Ensembl Gene Model | MGI Sequence Detail 94256 C57BL/6J ±  kb
transcript ENSMUST00000046521 Ensembl | MGI Sequence Detail 6102 Not Applicable  
polypeptide ENSMUSP00000046152 Ensembl | MGI Sequence Detail 1425 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 12
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:1919744, MGI:2441728, MGI:2684976
References
more
  • Summaries
    All 60
    Developmental Gene Expression 9
    Diseases 1
    Gene Ontology 11
    Phenotypes 23
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:321981 Shull LC, et al., PRDM paralogs antagonistically balance Wnt/beta-catenin activity during craniofacial chondrocyte differentiation. Development. 2022 Feb 15;149(4):dev200082
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory