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Defb41 Gene Detail
Summary
  • Symbol
    Defb41
  • Name
    defensin beta 41
  • Synonyms
    9230102D03Rik, Gm15386
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924923
    NCBI Gene: 77673
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:18321204-18335362 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 5.70 cM, cytoband A4
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    639 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924923
 protein coding gene Chr1:18321200-18335362 (-)
129S1/SvImJ MGP_129S1SvImJ_G0015866
 protein coding gene Chr1:15842548-15855709 (-)
A/J MGP_AJ_G0015847
 protein coding gene Chr1:15627261-15639300 (-)
AKR/J MGP_AKRJ_G0015806
 protein coding gene Chr1:15610781-15624743 (-)
BALB/cJ MGP_BALBcJ_G0015803
 protein coding gene Chr1:15312976-15326732 (-)
C3H/HeJ MGP_C3HHeJ_G0015637
 protein coding gene Chr1:15694288-15706845 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016257
 protein coding gene Chr1:16530320-16544964 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0013978
 protein coding gene Chr1:14046105-14057528 (-)
CAST/EiJ MGP_CASTEiJ_G0015218
 protein coding gene Chr1:15767730-15788627 (-)
CBA/J MGP_CBAJ_G0015610
 protein coding gene Chr1:16882260-16898638 (-)
DBA/2J MGP_DBA2J_G0015709
 protein coding gene Chr1:15204165-15218325 (-)
FVB/NJ MGP_FVBNJ_G0015714
 protein coding gene Chr1:14982065-14997539 (-)
LP/J MGP_LPJ_G0015781
 protein coding gene Chr1:16036407-16049160 (-)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0016304
 protein coding gene Chr1:15584043-15600146 (-)
PWK/PhJ MGP_PWKPhJ_G0015002
 protein coding gene Chr1:14953756-14972454 (-)
SPRET/EiJ MGP_SPRETEiJ_G0014783
 protein coding gene Chr1:15721348-15733776 (-)
WSB/EiJ MGP_WSBEiJ_G0015281
 protein coding gene Chr1:15576711-15591685 (-)



Homology
more
  • Human Ortholog
    DEFB110, defensin beta 110
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DEFB110, defensin beta 110
  • Synonyms
    DEFB-10, DEFB-11, DEFB111
  • Links
    NCBI Gene ID: 245913
    neXtProt AC: NX_Q30KQ9
    UniProt: Q30KQ9

  • Chr Location
    6p12.3; chr6:50009138-50021994 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    9 phenotypes from multigenic genotypes
    10 phenotype references
Mice heterozygous for a knock-in allele do not exhibit any phenotypic abnormalities or fertility defects.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000067773 Ensembl Gene Model | MGI Sequence Detail 14159 C57BL/6J ±  kb
transcript ENSMUST00000097817 Ensembl | MGI Sequence Detail 198 Not Applicable  
polypeptide ENSMUSP00000095426 Ensembl | MGI Sequence Detail 65 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 2
    cDNA 2

    Microarray probesets 2
Other
Accession IDs
less
MGI:3711868, MGI:3840135
References
more
  • Summaries
    All 32
    Gene Ontology 3
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:354625 Trigg NA, et al., Epididymal acquired sperm microRNAs modify post-fertilization embryonic gene expression. Cell Rep. 2024 Sep 24;43(9):114698
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory