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Ndor1 Gene Detail
Summary
  • Symbol
    Ndor1
  • Name
    NADPH dependent diflavin oxidoreductase 1
  • Synonyms
    4930447P04Rik, NR1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926047
    NCBI Gene: 78797
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:25134825-25145458 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 17.10 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    289 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1926047
 protein coding gene Chr2:25134825-25146034 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025431
 protein coding gene Chr2:23112619-23123820 (-)
A/J MGP_AJ_G0025408
 protein coding gene Chr2:22224211-22235411 (-)
AKR/J MGP_AKRJ_G0025378
 protein coding gene Chr2:22966110-22977310 (-)
BALB/cJ MGP_BALBcJ_G0025404
 protein coding gene Chr2:22334060-22345261 (-)
C3H/HeJ MGP_C3HHeJ_G0025165
 protein coding gene Chr2:22894329-22905530 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025848
 protein coding gene Chr2:23844245-23855446 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023259
 protein coding gene Chr2:21141897-21153524 (-)
CAST/EiJ MGP_CASTEiJ_G0024628
 protein coding gene Chr2:22777021-22788406 (-)
CBA/J MGP_CBAJ_G0025143
 protein coding gene Chr2:24684102-24695303 (-)
DBA/2J MGP_DBA2J_G0025276
 protein coding gene Chr2:22066829-22078029 (-)
FVB/NJ MGP_FVBNJ_G0025238
 protein coding gene Chr2:21806714-21817915 (-)
LP/J MGP_LPJ_G0025362
 protein coding gene Chr2:23055672-23066873 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025269
 protein coding gene Chr2:24886190-24897390 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025907
 protein coding gene Chr2:22914234-22925434 (-)
PWK/PhJ MGP_PWKPhJ_G0024376
 protein coding gene Chr2:21878110-21889403 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024176
 protein coding gene Chr2:23069801-23081067 (-)
WSB/EiJ MGP_WSBEiJ_G0024697
 protein coding gene Chr2:22983945-22995145 (-)



Homology
more
  • Human Ortholog
    NDOR1, NADPH dependent diflavin oxidoreductase 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NDOR1, NADPH dependent diflavin oxidoreductase 1
  • Synonyms
    bA350O14.9, CIAE1, NR1
  • Links
    NCBI Gene ID: 27158
    neXtProt AC: NX_Q9UHB4
    UniProt: Q9UHB4

  • Chr Location
    9q34.3; chr9:137205685-137219361 (+)  GRCh38
Human Diseases
less
  • Mutations/Alleles
    1 with disease annotations
  • References
    3 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    285 phenotypes from multigenic genotypes
    519 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    30
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
    62
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 78797 NCBI Gene Model | MGI Sequence Detail 10634 C57BL/6J ±  kb
transcript NM_001082476 RefSeq | MGI Sequence Detail 4757 C57BL/6  
polypeptide A2AI05 UniProt | EBI | MGI Sequence Detail 598 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    7 Sequences
  • Protein Ontology
    PR:000011057 NADPH-dependent diflavin oxidoreductase 1
    (term hierarchy)
  • EC
    1.18.1.-
  • InterPro Domains
    IPR017927 FAD-binding domain, ferredoxin reductase-type
    IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain
    IPR001094 Flavodoxin-like
    IPR008254 Flavodoxin/nitric oxide synthase
    IPR029039 Flavoprotein-like superfamily
    IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase
    IPR023173 NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily
    IPR028879 NADPH-dependent diflavin oxidoreductase 1
    IPR001433 Oxidoreductase FAD/NAD(P)-binding
    IPR017938 Riboflavin synthase-like beta-barrel
    IPR003097 Sulfite reductase [NADPH] flavoprotein alpha-component-like, FAD-binding
Molecular
Reagents
less
  • All nucleic 62
    cDNA 62

    Microarray probesets 3
Other
Accession IDs
less
MGI:3707330
References
more
  • Summaries
    All 546
    Developmental Gene Expression 1
    Diseases 3
    Gene Ontology 6
    Phenotypes 519
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:354844 Vardam-Kaur T, et al., The ATP-exporting channel Pannexin 1 promotes CD8(+) T cell effector and memory responses. iScience. 2024 Jul 19;27(7):110290
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory