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Fibp Gene Detail
Summary
  • Symbol
    Fibp
  • Name
    fibroblast growth factor (acidic) intracellular binding protein
  • Synonyms
    2010004G08Rik, 2010005N21Rik, 3010027N18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926233
    NCBI Gene: 58249
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:5510643-5515079 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 4.33 cM, cytoband A
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    194 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1926233
 protein coding gene Chr19:5510626-5515080 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024708
 protein coding gene Chr19:2429845-2434294 (+)
A/J MGP_AJ_G0024674
 protein coding gene Chr19:2295255-2299702 (+)
AKR/J MGP_AKRJ_G0024647
 protein coding gene Chr19:2353164-2357612 (+)
BALB/cJ MGP_BALBcJ_G0024674
 protein coding gene Chr19:2289009-2293457 (+)
C3H/HeJ MGP_C3HHeJ_G0024442
 protein coding gene Chr19:2362728-2367175 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025121
 protein coding gene Chr19:2485436-2489886 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022551
 protein coding gene Chr19:2197614-2202308 (+)
CAST/EiJ MGP_CASTEiJ_G0023914
 protein coding gene Chr19:2390190-2394618 (+)
CBA/J MGP_CBAJ_G0024414
 protein coding gene Chr19:2594829-2599280 (+)
DBA/2J MGP_DBA2J_G0024541
 protein coding gene Chr19:2274634-2279087 (+)
FVB/NJ MGP_FVBNJ_G0024508
 protein coding gene Chr19:2281409-2285858 (+)
LP/J MGP_LPJ_G0024627
 protein coding gene Chr19:2409309-2413759 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024538
 protein coding gene Chr19:2449505-2453945 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025169
 protein coding gene Chr19:2370982-2375432 (+)
PWK/PhJ MGP_PWKPhJ_G0023660
 protein coding gene Chr19:2311662-2316168 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023465
 protein coding gene Chr19:2355737-2360096 (+)
WSB/EiJ MGP_WSBEiJ_G0023976
 protein coding gene Chr19:2381895-2386350 (+)



Homology
more
  • Human Ortholog
    FIBP, FGF1 intracellular binding protein
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FIBP, FGF1 intracellular binding protein
  • Synonyms
    FGFIBP, FIBP-1, TROFAS
  • Links
    NCBI Gene ID: 9158
    neXtProt AC: NX_O43427
    UniProt: O43427

  • Chr Location
    11q13.1; chr11:65883740-65888531 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    7
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    71
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024911 Ensembl Gene Model | MGI Sequence Detail 4437 C57BL/6J ±  kb
transcript ENSMUST00000025847 Ensembl | MGI Sequence Detail 1215 Not Applicable  
polypeptide ENSMUSP00000025847 Ensembl | MGI Sequence Detail 364 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000007519 acidic fibroblast growth factor intracellular-binding protein
    (term hierarchy)
  • InterPro Domains
    IPR008614 Acidic fibroblast growth factor intracellular-binding protein
  • GlyGen
    Q9JI19 1 site, 1 N-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 72
    cDNA 72

    Microarray probesets 4
Other
Accession IDs
less
MGI:1913680, MGI:1924201, MGI:1924334
References
more
  • Summaries
    All 30
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:66718 Kolpakova E, et al., Organization, chromosomal localization and promoter analysis of the gene encoding human acidic fibroblast growth factor intracellular binding protein. Biochem J. 2000 Dec 15;352 Pt 3:629-35
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory