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Syt5 Gene Detail
Summary
  • Symbol
    Syt5
  • Name
    synaptotagmin V
  • Synonyms
    SytIX
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926368
    NCBI Gene: 53420
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:4542764-4550540 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 2.62 cM, cytoband A1
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    307 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1926368
 protein coding gene Chr7:4542764-4550540 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031550
 protein coding gene Chr7:1459924-1468424 (-)
A/J MGP_AJ_G0031524
 protein coding gene Chr7:1459661-1467426 (-)
AKR/J MGP_AKRJ_G0031453
 protein coding gene Chr7:1537489-1545087 (-)
BALB/cJ MGP_BALBcJ_G0031532
 protein coding gene Chr7:1525331-1533085 (-)
C3H/HeJ MGP_C3HHeJ_G0031253
 protein coding gene Chr7:1501829-1510816 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031993
 protein coding gene Chr7:1493319-1502249 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029117
 protein coding gene Chr7:1228357-1236727 (-)
CAST/EiJ MGP_CASTEiJ_G0030617
 protein coding gene Chr7:1440822-1450747 (-)
CBA/J MGP_CBAJ_G0031211
 protein coding gene Chr7:1693604-1707074 (-)
DBA/2J MGP_DBA2J_G0031370
 protein coding gene Chr7:1422784-1430385 (-)
FVB/NJ MGP_FVBNJ_G0031322
 protein coding gene Chr7:1406500-1414151 (-)
LP/J MGP_LPJ_G0031455
 protein coding gene Chr7:1551079-1558822 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031361
 protein coding gene Chr7:1626449-1634087 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032023
 protein coding gene Chr7:1440396-1448588 (-)
PWK/PhJ MGP_PWKPhJ_G0030345
 protein coding gene Chr7:1608921-1616802 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030170
 protein coding gene Chr7:1503007-1510824 (-)
WSB/EiJ MGP_WSBEiJ_G0030712
 protein coding gene Chr7:1457805-1465471 (-)



Homology
more
  • Human Ortholog
    SYT5, synaptotagmin 5
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SYT5, synaptotagmin 5
  • Links
    NCBI Gene ID: 6861
    neXtProt AC: NX_O00445
    UniProt: O00445

  • Chr Location
    19q; chr19:55171196-55180289 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 2 alleles in 1 genetic background
    1 phenotype from multigenic genotypes
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
About 50% of mice homozygous for a knock-out allele exhibit prenatal lethality.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    34
  • GO References
    13
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    905
  • Tissues
    109
  • cDNA Data
    17
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 53420 NCBI Gene Model | MGI Sequence Detail 7777 C57BL/6J ±  kb
transcript NM_001360421 RefSeq | MGI Sequence Detail 1790 C57BL/6  
polypeptide Q9R0N5 UniProt | EBI | MGI Sequence Detail 386 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 19
    cDNA 17
    Primer pair 1
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 47
    Developmental Gene Expression 4
    Gene Ontology 13
    Phenotypes 10
  • Earliest
    J:1973 Willison K, The mouse Brachyury gene and mesoderm formation. Trends Genet. 1990 Apr;6(4):104-5
  • Latest
    J:353608 Weingarten DJ, et al., Synaptotagmins 3 and 7 mediate the majority of asynchronous release from synapses in the cerebellum and hippocampus. Cell Rep. 2024 Aug 27;43(8):114595
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory