Pdgfra<tm1Sor> Targeted Allele Detail MGI Mouse (MGI:1926714)

Pdgfra^tm1Sor
Targeted Allele Detail

Summary

Symbol:	Pdgfra^tm1Sor
Name:	platelet derived growth factor receptor, alpha polypeptide; targeted mutation 1, Philippe Soriano
MGI ID:	MGI:1926714
Synonyms:	alphaR1
Gene:	Pdgfra Location: Chr5:75312953-75358876 bp, + strand Genetic Position: Chr5, 39.55 cM
Alliance:	Pdgfra^tm1Sor page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:41814
Parent Cell Line:	AK7 (ES Cell)
Strain of Origin:	129S4/SvJaeSor

Mutation
description

Allele Type:		Targeted (Null/knockout)
Mutations:		Insertion, Intragenic deletion
		Mutation details: Replacement of sequences encoding the first immunoglobulin domain with a loxP-flanked neomycin cassette. (J:41814)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Mice Carrying this Mutation:	14 assay results
In Structures Affected by this Mutation:	26 anatomical structure(s)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Pdgfra Mutation:	88 strains or lines available

Notes

Partial protein product detected in Western blots.

References

Original:	J:41814 Soriano P, The PDGF alpha receptor is required for neural crest cell development and for normal patterning of the somites. Development. 1997 JUL;124(14):2691-2700
All:	9 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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