Summary | Transgene origin | Transgene description | Expression | Recombinase activity | Phenotypes | Disease models | Tumor data | Find Mice (IMSR) | References

Symbol:	Tg(KRT5-cre)1Tak
Name:	transgene insertion 1, Junji Takeda
MGI ID:	MGI:1926815
Synonyms:	K5-Cre, (K5)-Cre, K5Cre, Keratin5Cre, Tg(Cre)1Tak
Transgene:	Tg(KRT5-cre)1Tak  Location: unknown
Alliance:	Tg(KRT5-cre)1Tak page

Strain of Origin:

(C57BL/6 x C3H)F2

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(KRT5-cre)1Tak expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Homolog in Mouse Note human KRT5 (3852) Krt5  (MGI:96702)   Mutation details: A 14kb fragment of human keratin 5 (KRT5) promoter was used to control the expression of Cre in keratinocytes. A nuclear localization signal was added to the 5' end of the Cre gene. (J:41746)

Activity:	Tissue activity of this recombinase allele
Driver:	KRT5 (human) Summary of all recombinase alleles driven by KRT5. Alliance human KRT5 gene page

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	22 assay results 3 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	6 anatomical structure(s)

List all tumor models in MMHCdb carrying Tg(KRT5-cre)1Tak

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:41746 Tarutani M, et al., Tissue-specific knockout of the mouse Pig-a gene reveals important roles for GPI-anchored proteins in skin development. Proc Natl Acad Sci U S A. 1997 Jul 8;94(14):7400-5
All:	137 reference(s)