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Ehd3 Gene Detail
Summary
  • Symbol
    Ehd3
  • Name
    EH-domain containing 3
  • Synonyms
    Ehd2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1928900
    NCBI Gene: 57440
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:74111836-74139088 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 45.20 cM, cytoband E2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    929 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1928900
 protein coding gene Chr17:74111129-74139089 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024021
 protein coding gene Chr17:76387352-76416376 (+)
A/J MGP_AJ_G0023979
 protein coding gene Chr17:74056949-74084715 (+)
AKR/J MGP_AKRJ_G0023948
 protein coding gene Chr17:75109929-75136753 (+)
BALB/cJ MGP_BALBcJ_G0023980
 protein coding gene Chr17:73969953-73998128 (+)
C3H/HeJ MGP_C3HHeJ_G0023744
 protein coding gene Chr17:76050316-76077378 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024426
 protein coding gene Chr17:79140249-79168308 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021870
 protein coding gene Chr17:69737710-69767471 (+)
CAST/EiJ MGP_CASTEiJ_G0023225
 protein coding gene Chr17:76517576-76549896 (+)
CBA/J MGP_CBAJ_G0023719
 protein coding gene Chr17:82422978-82450156 (+)
DBA/2J MGP_DBA2J_G0023848
 protein coding gene Chr17:72679838-72707060 (+)
FVB/NJ MGP_FVBNJ_G0023814
 protein coding gene Chr17:72175602-72203062 (+)
LP/J MGP_LPJ_G0023930
 protein coding gene Chr17:77142738-77170041 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023842
 protein coding gene Chr17:82256543-82284619 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024470
 protein coding gene Chr17:75622001-75649204 (+)
PWK/PhJ MGP_PWKPhJ_G0022971
 protein coding gene Chr17:72038252-72066961 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022782
 protein coding gene Chr17:72267708-72296924 (+)
WSB/EiJ MGP_WSBEiJ_G0023292
 protein coding gene Chr17:76472456-76500550 (+)



Homology
more
  • Human Ortholog
    EHD3, EH domain containing 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    EHD3, EH domain containing 3
  • Synonyms
    PAST3
  • Links
    NCBI Gene ID: 30845
    neXtProt AC: NX_Q9NZN3
    UniProt: Q9NZN3

  • Chr Location
    2p23.1; chr2:31234152-31269451 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    21 phenotypes from multigenic genotypes
    4 images
    6 phenotype references
Mice homozygous for a knock-out allele are healthy and fertile.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    50
  • GO References
    15
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    855
  • Tissues
    39
  • cDNA Data
    56
  • Literature Summary
    9
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 57440 NCBI Gene Model | MGI Sequence Detail 27253 C57BL/6J ±  kb
transcript NM_020578 RefSeq | MGI Sequence Detail 3658 ZRU/MplStud  
polypeptide Q9QXY6 UniProt | EBI | MGI Sequence Detail 535 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 56
    cDNA 56

    Microarray probesets 4
References
more
  • Summaries
    All 46
    Developmental Gene Expression 9
    Gene Ontology 15
    Phenotypes 6
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:348785 Zhang D, et al., Maternal Ezh1/2 deficiency impairs the function of mitochondria in mouse oocytes and early embryos. J Cell Physiol. 2024 Mar 26;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory