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Cdc42ep5 Gene Detail
Summary
  • Symbol
    Cdc42ep5
  • Name
    CDC42 effector protein 5
  • Synonyms
    1700027J19Rik, 2010007O02Rik, Borg3, CEP5
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929745
    NCBI Gene: 58804
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:4154259-4167830 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 2.40 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    445 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1929745
 protein coding gene Chr7:4154259-4167859 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031540
 protein coding gene Chr7:1074936-1091720 (-)
A/J MGP_AJ_G0031514
 protein coding gene Chr7:1053589-1067047 (-)
AKR/J MGP_AKRJ_G0031442
 protein coding gene Chr7:1110969-1124458 (-)
BALB/cJ MGP_BALBcJ_G0031522
 protein coding gene Chr7:1127118-1140746 (-)
C3H/HeJ MGP_C3HHeJ_G0031243
 protein coding gene Chr7:1107791-1123892 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031983
 protein coding gene Chr7:1106551-1119868 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029107
 protein coding gene Chr7:850470-865094 (-)
CAST/EiJ MGP_CASTEiJ_G0030607
 protein coding gene Chr7:1050231-1066485 (-)
CBA/J MGP_CBAJ_G0031201
 protein coding gene Chr7:1301276-1317889 (-)
DBA/2J MGP_DBA2J_G0031360
 protein coding gene Chr7:1034499-1051805 (-)
FVB/NJ MGP_FVBNJ_G0031312
 protein coding gene Chr7:1016184-1033379 (-)
LP/J MGP_LPJ_G0031445
 protein coding gene Chr7:1167237-1185307 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031351
 protein coding gene Chr7:1179572-1195412 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032013
 protein coding gene Chr7:1048398-1063271 (-)
PWK/PhJ MGP_PWKPhJ_G0030335
 protein coding gene Chr7:1237296-1251791 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030160
 protein coding gene Chr7:1177987-1191514 (-)
WSB/EiJ MGP_WSBEiJ_G0030702
 protein coding gene Chr7:1077557-1092966 (-)



Homology
more
  • Human Ortholog
    CDC42EP5, CDC42 effector protein 5
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CDC42EP5, CDC42 effector protein 5
  • Synonyms
    Borg3, CEP5
  • Links
    NCBI Gene ID: 148170
    neXtProt AC: NX_Q6NZY7
    UniProt: Q6NZY7

  • Chr Location
    19q13.42; chr19:54465026-54473296 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    25
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    39
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 58804 NCBI Gene Model | MGI Sequence Detail 13572 C57BL/6J ±  kb
transcript NM_021454 RefSeq | MGI Sequence Detail 870 C57BL/6  
polypeptide Q9Z0X0 UniProt | EBI | MGI Sequence Detail 150 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 40
    cDNA 40

    Microarray probesets 3
Other
Accession IDs
less
MGI:1917098, MGI:1919516, MGI:2142357
References
more
  • Summaries
    All 34
    Gene Ontology 6
    Phenotypes 8
  • Earliest
    J:65159 Joberty G, et al., The Borgs, a new family of Cdc42 and TC10 GTPase-interacting proteins. Mol Cell Biol. 1999 Oct;19(10):6585-97
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory