Summary | Mutation origin | Mutation description | Expression | Recombinase activity | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol: Myl1tm1(cre)Sjb Name: myosin, light polypeptide 1; targeted mutation 1, Steven J Burden MGI ID: MGI:1931135 Synonyms: Mlc1f-cre, mlccre, MLC-Cre, Mlcf-cre Gene: Myl1  Location: Chr1:66963454-66984563 bp, - strand  Genetic Position: Chr1, 33.71 cM Alliance: Myl1tm1(cre)Sjb page

Skeletal muscle analysis of Tfamtm1Lrsn/Tfamtm1Lrsn Myl1tm1(cre)Sjb/Myl1+ mice Show the 2 phenotype image(s) involving this allele.

Germline Transmission:	Earliest citation of germline transmission: J:67675
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Recombinase) Mutation:    Insertion   Myl1tm1(cre)Sjb expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Myl1 (MGI:97269)   Mutation details: Insertion of an NLS-cre gene into exon 1, immediately upstream of the initiator ATG. An adjacent lox-P flanked neomycin cassette was removed by Cre mediated recombination in the final allele. (J:67675)

Activity:	Tissue activity of this recombinase allele
Driver:	Myl1 (mouse) Summary of all recombinase alleles driven by Myl1. Alliance mouse Myl1 gene page

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

10 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Myl1 Mutation:	17 strains or lines available

Original:	J:67675 Bothe GW, et al., Selective expression of Cre recombinase in skeletal muscle fibers. Genesis. 2000 Feb;26(2):165-6
All:	126 reference(s)