Nkx3-2<tm1Bobh> Targeted Allele Detail MGI Mouse (MGI:1931319)

Nkx3-2^tm1Bobh
Targeted Allele Detail

Summary

Symbol:	Nkx3-2^tm1Bobh
Name:	NK3 homeobox 2; targeted mutation 1, Robert E Hill
MGI ID:	MGI:1931319
Synonyms:	Bapx1 -, Nkx3.2 -
Gene:	Nkx3-2 Location: Chr5:41918826-41921563 bp, - strand Genetic Position: Chr5, 22.58 cM
Alliance:	Nkx3-2^tm1Bobh page

Skeletal phenotypes of E18.5 Nkx3-2^tm1Bobh/Nkx3-2^tm1Bobh fetuses

Show the 3 phenotype image(s) involving this allele.

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:57112
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Mutation
description

Allele Type:		Targeted (Null/knockout)
Mutation:		Insertion
		Insertion of a neomycin cassette into the coding region of exon 1. (J:57112)
Inheritance:		Recessive

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Mice Carrying this Mutation:	22 assay results
In Structures Affected by this Mutation:	21 anatomical structure(s)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Nkx3-2 Mutation:	21 strains or lines available

References

Original:	J:57112 Lettice LA, et al., The mouse bagpipe gene controls development of axial skeleton, skull, and spleen. Proc Natl Acad Sci U S A. 1999 Aug 17;96(17):9695-700
All:	7 reference(s)

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