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Il13tm2Anjm
Targeted Allele Detail
Summary
Symbol: Il13tm2Anjm
Name: interleukin 13; targeted mutation 2, Andrew NJ McKenzie
MGI ID: MGI:1931804
Synonyms: IL13-, IL-13KO
Gene: Il13  Location: Chr11:53522151-53525529 bp, - strand  Genetic Position: Chr11, 31.98 cM
Alliance: Il13tm2Anjm page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:67965
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    A neomycin cassette was inserted into exon 3. (J:67965)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 6 strains available      Cell Lines: 0 lines available
Carrying any Il13 Mutation:  30 strains or lines available
References
Original:  J:67965 McKenzie GJ, et al., Impaired development of Th2 cells in IL-13-deficient mice. Immunity. 1998 Sep;9(3):423-32
All:  64 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory