Summary | Mutation origin | Mutation description | Expression | Recombinase activity | Phenotypes | Disease models | Find Mice (IMSR) | Notes | References

Symbol:	Foxg1tm1(cre)Skm
Name:	forkhead box G1; targeted mutation 1, Susan K McConnell
MGI ID:	MGI:1932522
Synonyms:	BF1-cre, Foxg1-, Foxg1-Cre, Foxg1:Cre, Foxg1Cre, FoxG1Cre, Foxg1KiCre, TgH(Foxg1-Cre)1Skm
Gene:	Foxg1  Location: Chr12:49429666-49433650 bp, + strand  Genetic Position: Chr12, 21.78 cM
Alliance:	Foxg1tm1(cre)Skm page

Germline Transmission:	Earliest citation of germline transmission: J:62916
Parent Cell Line:	HM-1 (ES Cell)
Strain of Origin:	129P2/OlaHsd-Hprt1b-m3

Allele Type:    Targeted (Null/knockout, Recombinase) Mutations:    Insertion, Intragenic deletion   Foxg1tm1(cre)Skm expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Foxg1 (MGI:1347464)   Mutation details: Most of the coding region was replaced with a cre gene and a neomycin cassette. The cre gene sequence was fused in-frame following the first 13 codons of the gene. The endogenous promoter is active in telencephalon, anterior optic vesicle, otic vesicle, facial and head ectoderm, olfactory epithelium, mid-hindbrain junction and pharyngeal pouches. (J:62916) Inheritance:    Recessive

Activity:	Tissue activity of this recombinase allele
Driver:	Foxg1 (mouse) Summary of all recombinase alleles driven by Foxg1. Comparative matrix view of recombinase activities Alliance mouse Foxg1 gene page

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	719 assay results 14 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	10 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Foxg1 Mutation:	29 strains or lines available

Original:	J:62916 Hebert JM, et al., Targeting of cre to the Foxg1 (BF-1) locus mediates loxP recombination in the telencephalon and other developing head structures. Dev Biol. 2000 Jun 15;222(2):296-306
All:	293 reference(s)