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Tex14 Gene Detail
Summary
  • Symbol
    Tex14
  • Name
    testis expressed gene 14 intercellular bridge forming factor
  • Feature Type
    protein coding gene
  • IDs
    MGI:1933227
    NCBI Gene: 83560
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:87295891-87446649 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 52.09 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    515 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1933227
 protein coding gene Chr11:87295839-87446649 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018904
 protein coding gene Chr11:89009563-89181408 (+)
A/J MGP_AJ_G0018871
 protein coding gene Chr11:85578178-85739933 (+)
AKR/J MGP_AKRJ_G0018841
 protein coding gene Chr11:88143185-88309237 (+)
BALB/cJ MGP_BALBcJ_G0018844
 protein coding gene Chr11:85979742-86136317 (+)
C3H/HeJ MGP_C3HHeJ_G0018658
 protein coding gene Chr11:88159962-88344864 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019296
 protein coding gene Chr11:91690402-91881472 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016929
 protein coding gene Chr11:82609403-82768922 (+)
CAST/EiJ MGP_CASTEiJ_G0018213
 protein coding gene Chr11:88868293-89036349 (+)
CBA/J MGP_CBAJ_G0018629
 protein coding gene Chr11:95550142-95736873 (+)
DBA/2J MGP_DBA2J_G0018737
 protein coding gene Chr11:85138194-85294047 (+)
FVB/NJ MGP_FVBNJ_G0018726
 protein coding gene Chr11:84643692-84801046 (+)
LP/J MGP_LPJ_G0018807
 protein coding gene Chr11:89501981-89674680 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018753
 protein coding gene Chr11:95604792-95801426 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019336
 protein coding gene Chr11:88373525-88546260 (+)
PWK/PhJ MGP_PWKPhJ_G0017983
 protein coding gene Chr11:85959675-86139728 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017775
 protein coding gene Chr11:87948435-88110501 (+)
WSB/EiJ MGP_WSBEiJ_G0018264
 protein coding gene Chr11:88283436-88423732 (+)



Homology
more
  • Human Ortholog
    TEX14, testis expressed 14, intercellular bridge forming factor
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TEX14, testis expressed 14, intercellular bridge forming factor
  • Synonyms
    CT113, SgK307, SPGF23
  • Links
    NCBI Gene ID: 56155
    neXtProt AC: NX_Q8IWB6
    UniProt: Q8IWB6

  • Chr Location
    17q22; chr17:58556678-58692055 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human TEX14 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 1 allele in 2 genetic backgrounds
    3 images
    26 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Males homozygous for a targeted allele are infertile due to spermatogenic failure.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    28
  • GO References
    12
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    717
  • Tissues
    5
  • cDNA Data
    13
  • Literature Summary
    7
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000010342 Ensembl Gene Model | MGI Sequence Detail 150759 C57BL/6J ±  kb
    transcript ENSMUST00000060835 Ensembl | MGI Sequence Detail 4763 Not Applicable  
    polypeptide ENSMUSP00000054444 Ensembl | MGI Sequence Detail 1450 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 15
      Genomic 1
      cDNA 13
      Primer pair 1

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:2144681
    References
    more
    • Summaries
      All 61
      Developmental Gene Expression 7
      Gene Ontology 12
      Phenotypes 26
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:346053 Zhang J, et al., Regulation of meiotic telomere dynamics through membrane fluidity promoted by AdipoR2-ELOVL2. Nat Commun. 2024 Mar 14;15(1):2315
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory