Lfng<tm1Grid> Targeted Allele Detail MGI Mouse (MGI:1933734)

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Lfng^tm1Grid
Targeted Allele Detail

Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Summary

Symbol:	Lfng^tm1Grid
Name:	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; targeted mutation 1, Tom Gridley
MGI ID:	MGI:1933734
Synonyms:	Lfng^-, Lfng^LacZ
Gene:	Lfng Location: Chr5:140593096-140601300 bp, + strand Genetic Position: Chr5, 79.15 cM
Alliance:	Lfng^tm1Grid page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:48810
Parent Cell Line:	CJ7 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation
description

Allele Type:		Targeted (Null/knockout, Reporter)
Mutations:		Insertion, Intragenic deletion
		A lacZ-neomycin resistance cassette replaced 0.7kb of the gene including most of exon 1. (J:48810)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Mice Carrying this Mutation:	4 assay results
In Structures Affected by this Mutation:	9 anatomical structure(s)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any Lfng Mutation:	32 strains or lines available

References

Original:	J:48810 Zhang N, et al., Defects in somite formation in lunatic fringe-deficient mice. Nature. 1998 Jul 23;394(6691):374-7
All:	17 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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