About   Help   FAQ
Dleu2 Gene Detail
Summary
  • Symbol
    Dleu2
  • Name
    deleted in lymphocytic leukemia, 2
  • Synonyms
    1810047A16Rik, 4932411A06Rik, 7730401J12Rik, Alt1, Gm9069, Leu2
  • Feature Type
    lncRNA gene
  • IDs
    MGI:1934030
    NCBI Gene: 668253
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:61840285-61919822 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 33.16 cM
  • Mapping Data
    6 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1673 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1934030
 lncRNA gene Chr14:61840265-61919822 (-)
129S1/SvImJ MGP_129S1SvImJ_G0015270
 unclassified non-coding RNA gene Chr14:55989976-56080260 (-)
A/J MGP_AJ_G0015244
 unclassified non-coding RNA gene Chr14:54770427-54851179 (-)
AKR/J MGP_AKRJ_G0015207
 unclassified non-coding RNA gene Chr14:56719600-56809397 (-)
BALB/cJ MGP_BALBcJ_G0015208
 unclassified non-coding RNA gene Chr14:54726112-54806297 (-)
C3H/HeJ MGP_C3HHeJ_G0015032
 unclassified non-coding RNA gene Chr14:56351702-56439590 (-)
C57BL/6NJ MGP_C57BL6NJ_G0015663
 unclassified non-coding RNA gene Chr14:58717186-58803063 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0013404
 unclassified non-coding RNA gene Chr14:52743460-52821144 (-)
CAST/EiJ MGP_CASTEiJ_G0014583
 unclassified non-coding RNA gene Chr14:52750935-52834699 (-)
CBA/J MGP_CBAJ_G0015012
 unclassified non-coding RNA gene Chr14:60406949-60502895 (-)
DBA/2J MGP_DBA2J_G0015105
 unclassified non-coding RNA gene Chr14:54426820-54517708 (-)
FVB/NJ MGP_FVBNJ_G0015113
 unclassified non-coding RNA gene Chr14:53855054-53934389 (-)
LP/J MGP_LPJ_G0015186
 unclassified non-coding RNA gene Chr14:57023901-57110911 (-)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0015702
 unclassified non-coding RNA gene Chr14:55869003-55953447 (-)
PWK/PhJ MGP_PWKPhJ_G0014375
 unclassified non-coding RNA gene Chr14:51100592-51182534 (-)
SPRET/EiJ MGP_SPRETEiJ_G0014162
 unclassified non-coding RNA gene Chr14:51795846-51880484 (-)
WSB/EiJ MGP_WSBEiJ_G0014690
 unclassified non-coding RNA gene Chr14:56188879-56270820 (-)



Homology
less
Human Diseases
less
  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotype references
  • All Mutations and Alleles
    38
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    33
  • Targeted
    3
  • Genomic Mutations
    4 involving Dleu2
  • Find Mice (IMSR)
    4 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    711
  • Tissues
    5
  • cDNA Data
    20
  • Literature Summary
    2
Sequences &
Gene Models
less
  • All Sequences
    99
  • RefSeq
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 668253 NCBI Gene Model | MGI Sequence Detail 79538 C57BL/6J ±  kb
transcript NR_028264 RefSeq | MGI Sequence Detail 1708 ZRU/MplStud  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 23
    Genomic 1
    cDNA 21
    Primer pair 1

    Microarray probesets 7
Other
Accession IDs
less
MGI:1353583, MGI:1917069, MGI:2145689, MGI:2441725, MGI:3779832
References
more
  • Summaries
    All 40
    Developmental Gene Expression 2
    Diseases 2
    Gene Ontology 1
    Phenotypes 15
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
  • Latest
    J:346989 Tang S, et al., A lncRNA Dleu2-encoded peptide relieves autoimmunity by facilitating Smad3-mediated Treg induction. EMBO Rep. 2024 Mar;25(3):1208-1232
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory