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Pitx1tm1Rsd
Targeted Allele Detail
Summary
Symbol: Pitx1tm1Rsd
Name: paired-like homeodomain transcription factor 1; targeted mutation 1, Michael G Rosenfeld
MGI ID: MGI:1934200
Gene: Pitx1  Location: Chr13:55972864-55984005 bp, - strand  Genetic Position: Chr13, 30.06 cM
Alliance: Pitx1tm1Rsd page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:53310
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: The sequences encoding the homeodomain and most of the 3' coding sequence of this gene were replaced with a lacZ/neo-derived cassette via homologous recombination. (J:53310)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 3 assay results
2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 16 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pitx1 Mutation:  11 strains or lines available
References
Original:  J:53310 Szeto DP, et al., Role of the Bicoid-related homeodomain factor Pitx1 in specifying hindlimb morphogenesis and pituitary development. Genes Dev. 1999 Feb 15;13(4):484-94
All:  7 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory