Amn<amn> Transgenic Allele Detail MGI Mouse (MGI:2135304)

Amn^amn
Transgenic Allele Detail

Summary

Symbol:	Amn^amn
Name:	amnionless
MGI ID:	MGI:2135304
Synonyms:	amn, Tg(CD8A)T81-3Ehl
Gene:	Amn Location: Chr12:111237530-111242860 bp, + strand Genetic Position: Chr12, 60.94 cM
Alliance:	Amn^amn page

Transgene
origin

Strain of Origin:

C57BL/6J

Transgene
description

Transgene Type:		Transgenic
Mutation:		Insertion
		Mutation details: Integration of three to five copies of the human CD8A transgene into the Amn gene caused a small deletion at the insertion site. Heterozygote mutant mice express low levels of human CD8A mRNA in spleen, thymus, and brain. (J:68615)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Structures Affected by this Mutation:

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Amn Mutation:	19 strains or lines available

Notes

At one time amn was thought to be an allele of Traf3 J:34163.

References

Original:	J:34163 Wang X, et al., A candidate gene for the amnionless gastrulation stage mouse mutation encodes a TRAF-related protein. Dev Biol. 1996 Jul 10;177(1):274-90
All:	5 reference(s)

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