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Fgf9tm1Dor
Targeted Allele Detail
Summary
Symbol: Fgf9tm1Dor
Name: fibroblast growth factor 9; targeted mutation 1, David Ornitz
MGI ID: MGI:2135961
Synonyms: Fgf9-
Gene: Fgf9  Location: Chr14:58308543-58350311 bp, + strand  Genetic Position: Chr14, 30.51 cM, cytoband D
Alliance: Fgf9tm1Dor page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:68379
Parent Cell Line:  SM1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: Replacement of 500 bp of genomic sequence with a neomycin resistance cassette, resulting in a deletion eliminating 224 bp of the 277 bp in the protein-coding region of exon 1 and extending into the first intron. (J:68379)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 55 assay results
In Structures Affected by this Mutation: 15 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fgf9 Mutation:  17 strains or lines available
References
Original:  J:68379 Colvin JS, et al., Male-to-female sex reversal in mice lacking fibroblast growth factor 9. Cell. 2001 Mar 23;104(6):875-89
All:  39 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory