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Hoxa11tm1Ssp
Targeted Allele Detail
Summary
Symbol: Hoxa11tm1Ssp
Name: homeobox A11; targeted mutation 1, S Steven Potter
MGI ID: MGI:2135973
Synonyms: Hoxa11-, Hox A11-, Hoxa-11CIN
Gene: Hoxa11  Location: Chr6:52219086-52222784 bp, - strand  Genetic Position: Chr6, 25.4 cM
Alliance: Hoxa11tm1Ssp page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:16079
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
    Deletion of a 2.7 kb region including the 3' portion of the gene encoding the homeobox domain. (J:16079)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 31 assay results
2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 17 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hoxa11 Mutation:  11 strains or lines available
References
Original:  J:16079 Small KM, et al., Homeotic transformations and limb defects in Hox A11 mutant mice. Genes Dev. 1993 Dec;7(12A):2318-28
All:  19 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory