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Emx1tm1Sia
Targeted Allele Detail
Summary
Symbol: Emx1tm1Sia
Name: empty spiracles homeobox 1; targeted mutation 1, Shinichi Aizawa
MGI ID: MGI:2136349
Synonyms: Emx1HD/HD
Gene: Emx1  Location: Chr6:85164913-85181445 bp, + strand  Genetic Position: Chr6, 37.21 cM
Alliance: Emx1tm1Sia page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:38397
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation details: A neomycin cassette was inserted into the second exon, in front of the sequences encoding the homeobox domain. (J:38397)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 74 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Emx1 Mutation:  34 strains or lines available
References
Original:  J:38397 Yoshida M, et al., Emx1 and Emx2 functions in development of dorsal telencephalon. Development. 1997 Jan;124(1):101-11
All:  8 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory