Emx2<tm1Sia> Targeted Allele Detail MGI Mouse (MGI:2136350)

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Emx2^tm1Sia
Targeted Allele Detail

Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Summary

Symbol:	Emx2^tm1Sia
Name:	empty spiracles homeobox 2; targeted mutation 1, Shinichi Aizawa
MGI ID:	MGI:2136350
Synonyms:	Emx2^HD/HD
Gene:	Emx2 Location: Chr19:59447122-59453789 bp, + strand Genetic Position: Chr19, 56.28 cM
Alliance:	Emx2^tm1Sia page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:38397
Parent Cell Line:	TT2 (ES Cell)
Strain of Origin:	(C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation
description

Allele Type:		Targeted (Null/knockout)
Mutation:		Insertion
		Mutation details: A neomycin cassette was inserted into the second exon, in front of the sequences encoding the homeobox domain. (J:38397)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Mice Carrying this Mutation:	251 assay results 2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	16 anatomical structure(s)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any Emx2 Mutation:	24 strains or lines available

References

Original:	J:38397 Yoshida M, et al., Emx1 and Emx2 functions in development of dorsal telencephalon. Development. 1997 Jan;124(1):101-11
All:	17 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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