Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | Notes | References

Symbol:	Gdnftm1Lmgd
Name:	glial cell line derived neurotrophic factor; targeted mutation 1, Laboratory of Mammalian Genes and Development, Heiner Westphal
MGI ID:	MGI:2136846
Synonyms:	Gdnf-
Gene:	Gdnf  Location: Chr15:7840327-7867056 bp, + strand  Genetic Position: Chr15, 3.8 cM
Alliance:	Gdnftm1Lmgd page

Germline Transmission:	Earliest citation of germline transmission: J:33810
Parent Cell Line:	Other (see notes) (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     Replacement of part of the third exon with a neomycin cassette. (J:33810)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	14 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	20 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gdnf Mutation:	19 strains or lines available

Original:	J:33810 Pichel JG, et al., Defects in enteric innervation and kidney development in mice lacking GDNF. Nature. 1996 Jul 4;382(6586):73-6
All:	47 reference(s)