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Tmem62 Gene Detail
Summary
  • Symbol
    Tmem62
  • Name
    transmembrane protein 62
  • Synonyms
    B830009D23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2139461
    NCBI Gene: 96957
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:120807498-120838333 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 60.37 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    685 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2139461
 protein coding gene Chr2:120806959-120838333 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026376
 protein coding gene Chr2:123849320-123884551 (+)
A/J MGP_AJ_G0026337
 protein coding gene Chr2:118785266-118817033 (+)
AKR/J MGP_AKRJ_G0026316
 protein coding gene Chr2:122114983-122149433 (+)
BALB/cJ MGP_BALBcJ_G0026350
 protein coding gene Chr2:119020548-119051356 (+)
C3H/HeJ MGP_C3HHeJ_G0026096
 protein coding gene Chr2:122603361-122636199 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026797
 protein coding gene Chr2:127920707-127952738 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024177
 protein coding gene Chr2:113828479-113859659 (+)
CAST/EiJ MGP_CASTEiJ_G0025558
 protein coding gene Chr2:122913665-122950111 (+)
CBA/J MGP_CBAJ_G0026072
 protein coding gene Chr2:132364941-132409271 (+)
DBA/2J MGP_DBA2J_G0026211
 protein coding gene Chr2:118184826-118217629 (+)
FVB/NJ MGP_FVBNJ_G0026173
 protein coding gene Chr2:117006282-117036999 (+)
LP/J MGP_LPJ_G0026312
 protein coding gene Chr2:124113769-124145511 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026192
 protein coding gene Chr2:136675932-136709361 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026852
 protein coding gene Chr2:122236482-122269563 (+)
PWK/PhJ MGP_PWKPhJ_G0025294
 protein coding gene Chr2:117786233-117817673 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025093
 protein coding gene Chr2:121453206-121486651 (+)
WSB/EiJ MGP_WSBEiJ_G0025627
 protein coding gene Chr2:123064653-123096809 (+)



Homology
more
  • Human Ortholog
    TMEM62, transmembrane protein 62
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM62, transmembrane protein 62
  • Links
    NCBI Gene ID: 80021
    neXtProt AC: NX_Q0P6H9
    UniProt: Q0P6H9

  • Chr Location
    15q15.2; chr15:43123279-43185144 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    47
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000054484 Ensembl Gene Model | MGI Sequence Detail 30836 C57BL/6J ±  kb
    transcript ENSMUST00000067582 Ensembl | MGI Sequence Detail 2921 Not Applicable  
    polypeptide ENSMUSP00000064310 Ensembl | MGI Sequence Detail 643 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      3 Sequences
    • Protein Ontology
      PR:000032190 transmembrane protein 62
      (term hierarchy)
    • InterPro Domains
      IPR004843 Calcineurin-like phosphoesterase domain, ApaH type
      IPR029052 Metallo-dependent phosphatase-like
      IPR041871 TMEM62, metallophosphatase domain
    • GlyGen
      Q8BXJ9 4 sites, 5 N-linked glycans (4 sites)
    Molecular
    Reagents
    less
    • All nucleic 48
      Genomic 1
      cDNA 47

      Microarray probesets 6
    References
    more
    • Summaries
      All 31
      Gene Ontology 2
      Phenotypes 8
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory