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H4c14 Gene Detail
Summary
  • Symbol
    H4c14
  • Name
    H4 clustered histone 14
  • Synonyms
    H4, Hist2h4, X04652
  • Feature Type
    protein coding gene
  • IDs
    MGI:2140113
    NCBI Gene: 97122
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:96170250-96170633 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 41.70 cM, cytoband F1-F2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    137 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2140113
 protein coding gene Chr3:96168998-96170633 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027613
 protein coding gene Chr3:97074497-97076073 (-)
A/J MGP_AJ_G0027573
 protein coding gene Chr3:94027195-94028832 (-)
AKR/J MGP_AKRJ_G0027541
 protein coding gene Chr3:96234246-96235875 (-)
BALB/cJ MGP_BALBcJ_G0027584
 protein coding gene Chr3:93804234-93805862 (-)
C3H/HeJ MGP_C3HHeJ_G0027317
 protein coding gene Chr3:96515635-96517268 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028031
 protein coding gene Chr3:100633156-100634785 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025373
 protein coding gene Chr3:90347192-90348604 (-)
CAST/EiJ MGP_CASTEiJ_G0026769
 protein coding gene Chr3:95829075-95830738 (-)
CBA/J MGP_CBAJ_G0027293
 protein coding gene Chr3:104320267-104322007 (-)
DBA/2J MGP_DBA2J_G0027434
 protein coding gene Chr3:93328043-93329672 (-)
FVB/NJ MGP_FVBNJ_G0027405
 protein coding gene Chr3:91388483-91390114 (-)
LP/J MGP_LPJ_G0027541
 protein coding gene Chr3:98381889-98383528 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027431
 protein coding gene Chr3:110410224-110411847 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028085
 protein coding gene Chr3:95864898-95866526 (-)
PWK/PhJ MGP_PWKPhJ_G0026498
 protein coding gene Chr3:93227598-93229038 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026319
 protein coding gene Chr3:94164961-94166387 (-)
WSB/EiJ MGP_WSBEiJ_G0026851
 protein coding gene Chr3:96260385-96262024 (-)



Homology
more
  • Human Ortholog
    H4C3, H4 clustered histone 3
  • Vertebrate Orthologs
    16
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    H4C3, H4 clustered histone 3
  • Synonyms
    dJ221C16.1, H4-16, H4C1, H4C11, H4C12, H4C13, H4C14, H4C15, H4C16, H4C2, H4C4, H4C5, H4C6, H4C8, H4C9, H4FG, H4/g, HIST1H4C, TEBIVANED1, TEVANED1
  • Links
    NCBI Gene ID: 8364
    neXtProt AC: NX_P62805
    UniProt: P62805

  • Chr Location
    6p22.2; chr6:26103933-26104337 (+)  GRCh38
  • Human Ortholog
    H4C5, H4 clustered histone 5
  • Synonyms
    H4-16, H4C1, H4C11, H4C12, H4C13, H4C14, H4C15, H4C16, H4C2, H4C3, H4C4, H4C6, H4C8, H4C9, H4FJ, H4/j, HIST1H4E, TEBIVANED3, TEVANED3
  • Links
    NCBI Gene ID: 8367
    neXtProt AC: NX_P62805
    UniProt: P62805

  • Chr Location
    6p22.2; chr6:26204610-26205021 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Radiation induced
    1
  • Genomic Mutations
    2 involving H4c14
  • Find Mice (IMSR)
    1 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    750
  • Tissues
    25
  • cDNA Data
    4
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 97122 NCBI Gene Model | MGI Sequence Detail 384 C57BL/6J ±  kb
transcript NM_033596 RefSeq | MGI Sequence Detail 384 C57BL/6  
polypeptide P62806 UniProt | EBI | MGI Sequence Detail 103 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 5
    cDNA 4
    Primer pair 1

    Microarray probesets 1
Other
Accession IDs
less
MGI:6325011
References
more
  • Summaries
    All 31
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:33128 Seiler-Tuyns A, et al., Structure and expression in L-cells of a cloned H4 histone gene of the mouse. J Mol Biol. 1981 Oct 5;151(4):607-25
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory