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Mgat4b Gene Detail
Summary
  • Symbol
    Mgat4b
  • Name
    mannoside acetylglucosaminyltransferase 4, isoenzyme B
  • Feature Type
    protein coding gene
  • IDs
    MGI:2143974
    NCBI Gene: 103534
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:50116162-50125930 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 30.37 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    254 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2143974
 protein coding gene Chr11:50101717-50125930 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018244
 protein coding gene Chr11:49377256-49403714 (+)
A/J MGP_AJ_G0018212
 protein coding gene Chr11:47483286-47507642 (+)
AKR/J MGP_AKRJ_G0018182
 protein coding gene Chr11:48994312-49019533 (+)
BALB/cJ MGP_BALBcJ_G0018182
 protein coding gene Chr11:47762632-47787006 (+)
C3H/HeJ MGP_C3HHeJ_G0017995
 protein coding gene Chr11:49000695-49025717 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018633
 protein coding gene Chr11:50839386-50866525 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016285
 protein coding gene Chr11:45102602-45127573 (+)
CAST/EiJ MGP_CASTEiJ_G0017557
 protein coding gene Chr11:48969897-48997730 (+)
CBA/J MGP_CBAJ_G0017970
 protein coding gene Chr11:53199959-53224042 (+)
DBA/2J MGP_DBA2J_G0018077
 protein coding gene Chr11:47282689-47306926 (+)
FVB/NJ MGP_FVBNJ_G0018071
 protein coding gene Chr11:46907553-46933287 (+)
LP/J MGP_LPJ_G0018152
 protein coding gene Chr11:49710648-49738621 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018096
 protein coding gene Chr11:54725997-54753954 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018677
 protein coding gene Chr11:49101119-49128865 (+)
PWK/PhJ MGP_PWKPhJ_G0017335
 protein coding gene Chr11:47682719-47711028 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017130
 protein coding gene Chr11:48796421-48820443 (+)
WSB/EiJ MGP_WSBEiJ_G0017610
 protein coding gene Chr11:48740497-48766380 (+)



Homology
more
  • Human Ortholog
    MGAT4B, alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MGAT4B, alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
  • Synonyms
    GNT-IV, GNT-IVB
  • Links
    NCBI Gene ID: 11282
    neXtProt AC: NX_Q9UQ53
    UniProt: Q9UQ53

  • Chr Location
    5q35.3; chr5:179797597-179806952 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotypes from 2 alleles in 2 genetic backgrounds
    1 phenotype from multigenic genotypes
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a floxed targeted allele are viable and do not display any gross physical or behavioral abnormalities.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    838
  • Tissues
    102
  • cDNA Data
    71
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 103534 NCBI Gene Model | MGI Sequence Detail 9769 C57BL/6J ±  kb
    transcript NM_145926 RefSeq | MGI Sequence Detail 2429 C57BL/6  
    polypeptide Q812F8 UniProt | EBI | MGI Sequence Detail 548 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 71
      cDNA 71

      Microarray probesets 2
    References
    more
    • Summaries
      All 32
      Developmental Gene Expression 3
      Gene Ontology 7
      Phenotypes 8
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory