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Pex12 Gene Detail
Summary
  • Symbol
    Pex12
  • Name
    peroxisomal biogenesis factor 12
  • Feature Type
    protein coding gene
  • IDs
    MGI:2144177
    NCBI Gene: 103737
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:83182757-83189849 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 50.30 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    209 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2144177
 protein coding gene Chr11:83182757-83193412 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018844
 protein coding gene Chr11:84614259-84622199 (-)
A/J MGP_AJ_G0018811
 protein coding gene Chr11:81402888-81410828 (-)
AKR/J MGP_AKRJ_G0018781
 protein coding gene Chr11:83823682-83831621 (-)
BALB/cJ MGP_BALBcJ_G0018784
 protein coding gene Chr11:81813560-81821504 (-)
C3H/HeJ MGP_C3HHeJ_G0018598
 protein coding gene Chr11:83876781-83884721 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019236
 protein coding gene Chr11:87211827-87219771 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016870
 protein coding gene Chr11:78529566-78537997 (-)
CAST/EiJ MGP_CASTEiJ_G0018153
 protein coding gene Chr11:84463840-84472954 (-)
CBA/J MGP_CBAJ_G0018569
 protein coding gene Chr11:90988409-90996349 (-)
DBA/2J MGP_DBA2J_G0018677
 protein coding gene Chr11:81000501-81008444 (-)
FVB/NJ MGP_FVBNJ_G0018666
 protein coding gene Chr11:80481861-80489805 (-)
LP/J MGP_LPJ_G0018747
 protein coding gene Chr11:85172953-85180893 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018693
 protein coding gene Chr11:91151653-91159597 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019276
 protein coding gene Chr11:84087793-84095738 (-)
PWK/PhJ MGP_PWKPhJ_G0017922
 protein coding gene Chr11:81759569-81767761 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017714
 protein coding gene Chr11:83635945-83644802 (-)
WSB/EiJ MGP_WSBEiJ_G0018204
 protein coding gene Chr11:83960890-83968962 (-)



Homology
more
  • Human Ortholog
    PEX12, peroxisomal biogenesis factor 12
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PEX12, peroxisomal biogenesis factor 12
  • Synonyms
    PAF-3, PBD3A
  • Links
    NCBI Gene ID: 5193
    neXtProt AC: NX_O00623
    UniProt: O00623

  • Chr Location
    17q12; chr17:35574795-35578863 (-)  GRCh38
Human Diseases
more
  • Diseases
    2 with human PEX12 associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    16 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    740
  • Tissues
    4
  • cDNA Data
    10
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 103737 NCBI Gene Model | MGI Sequence Detail 7093 C57BL/6J ±  kb
transcript NM_001364762 RefSeq | MGI Sequence Detail 2424 C57BL/6  
polypeptide Q8VC48 UniProt | EBI | MGI Sequence Detail 359 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 3
References
more
  • Summaries
    All 41
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 16
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:174216 Terzian T, et al., Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models. J Pathol. 2011 Aug;224(4):540-52
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory