About   Help   FAQ
Tcf21tm1Jrt
Targeted Allele Detail
Summary
Symbol: Tcf21tm1Jrt
Name: transcription factor 21; targeted mutation 1, Janet Rossant
MGI ID: MGI:2148207
Synonyms: pod1-, pod1/lacZ, Tcf21LacZ
Gene: Tcf21  Location: Chr10:22693162-22696042 bp, - strand  Genetic Position: Chr10, 10.33 cM
Alliance: Tcf21tm1Jrt page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:55785
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: Replacement of the initiation codon and sequences encoding the bHLH domain with an in-frame lacZ gene and neomycin resistance cassette. (J:55785)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 2 assay results
In Structures Affected by this Mutation: 23 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tcf21 Mutation:  16 strains or lines available
References
Original:  J:55785 Quaggin SE, et al., The basic-helix-loop-helix protein pod1 is critically important for kidney and lung organogenesis. Development. 1999 Dec;126(24):5771-83
All:  12 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory