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Ifit1bl2 Gene Detail
Summary
  • Symbol
    Ifit1bl2
  • Name
    interferon induced protein with tetratricopeptide repeats 1B like 2
  • Synonyms
    2010002M12Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2148249
    NCBI Gene: 112419
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:34594449-34618143 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 29.76 cM, cytoband C3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    363 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2148249
 protein coding gene Chr19:34594446-34618163 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025063
 protein coding gene Chr19:33372732-33399934 (-)
A/J MGP_AJ_G0025039
 protein coding gene Chr19:31749429-31784467 (-)
AKR/J MGP_AKRJ_G0025007
 protein coding gene Chr19:32853566-32879122 (-)
BALB/cJ MGP_BALBcJ_G0025037
 protein coding gene Chr19:31875664-31900267 (-)
C3H/HeJ MGP_C3HHeJ_G0024796
 protein coding gene Chr19:32935045-32960695 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025478
 protein coding gene Chr19:34373288-34399214 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022893
 protein coding gene Chr19:31155356-31161963 (-)
CAST/EiJ MGP_CASTEiJ_G0024263
 protein coding gene Chr19:32680765-32708215 (-)
CBA/J MGP_CBAJ_G0024773
 protein coding gene Chr19:35954390-35982825 (-)
DBA/2J MGP_DBA2J_G0024905
 protein coding gene Chr19:31658899-31683813 (-)
FVB/NJ MGP_FVBNJ_G0024866
 protein coding gene Chr19:31485328-31509065 (-)
LP/J MGP_LPJ_G0024991
 protein coding gene Chr19:33495637-33523940 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024896
 protein coding gene Chr19:35732528-35769039 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025536
 protein coding gene Chr19:32935785-32945019 (-)
PWK/PhJ MGP_PWKPhJ_G0024014
 protein coding gene Chr19:31440177-31442741 (-)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0024330
 protein coding gene Chr19:33005928-33032355 (-)



Homology
more
  • Human Ortholog
    IFIT1, interferon induced protein with tetratricopeptide repeats 1
  • Vertebrate Orthologs
    8
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IFIT1, interferon induced protein with tetratricopeptide repeats 1
  • Synonyms
    C56, G10P1, IFI-56, IFI56, IFI-56K, IFIT-1, IFNAI1, ISG56, P56, RNM561
  • Links
    NCBI Gene ID: 3434
    neXtProt AC: NX_P09914
    UniProt: P09914

  • Chr Location
    10q23.31; chr10:89392546-89406487 (+)  GRCh38
  • Human Ortholog
    IFIT1B, interferon induced protein with tetratricopeptide repeats 1B
  • Synonyms
    bA149I23.6, IFIT1L
  • Links
    NCBI Gene ID: 439996
    neXtProt AC: NX_Q5T764
    UniProt: Q5T764

  • Chr Location
    10q23.31; chr10:89378056-89385205 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    3 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    9
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000067297 Ensembl Gene Model | MGI Sequence Detail 23695 C57BL/6J ±  kb
    transcript ENSMUST00000087357 Ensembl | MGI Sequence Detail 3367 Not Applicable  
    polypeptide ENSMUSP00000093816 Ensembl | MGI Sequence Detail 466 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • InterPro Domains
      IPR011990 Tetratricopeptide-like helical domain superfamily
      IPR019734 Tetratricopeptide repeat
    • GlyGen
      Q3U687 1 site, 1 N-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 9
      cDNA 9

      Microarray probesets 1
    Other
    Accession IDs
    less
    MGI:2147726
    References
    more
    • Summaries
      All 26
      Gene Ontology 2
      Phenotypes 3
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory