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Ly6g6d Gene Detail
Summary
  • Symbol
    Ly6g6d
  • Name
    lymphocyte antigen 6 family member G6D
  • Synonyms
    A930024F17Rik, G6d, G6f, MEGT1, NG25, NG32
  • Feature Type
    protein coding gene
  • IDs
    MGI:2148931
    NCBI Gene: 114654
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:35290419-35297041 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 17, 18.59 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2148931
protein coding gene Chr17:35290318-35300215 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023613
protein coding gene Chr17:35212759-35219381 (-)
A/J MGP_AJ_G0023573
protein coding gene Chr17:34045144-34051810 (-)
AKR/J MGP_AKRJ_G0023541
protein coding gene Chr17:34519723-34526382 (-)
BALB/cJ MGP_BALBcJ_G0023579
protein coding gene Chr17:34181818-34188560 (-)
C3H/HeJ MGP_C3HHeJ_G0023340
protein coding gene Chr17:34912516-34919227 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024018
protein coding gene Chr17:36548191-36554813 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021499
protein coding gene Chr17:31812091-31819617 (-)
CAST/EiJ MGP_CASTEiJ_G0022837
protein coding gene Chr17:34915190-34921756 (-)
CBA/J MGP_CBAJ_G0023318
protein coding gene Chr17:38055278-38061897 (-)
DBA/2J MGP_DBA2J_G0023446
protein coding gene Chr17:33366040-33372706 (-)
FVB/NJ MGP_FVBNJ_G0023413
protein coding gene Chr17:33203471-33210111 (-)
LP/J MGP_LPJ_G0023523
protein coding gene Chr17:35536946-35543568 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023435
protein coding gene Chr17:36992572-37000319 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024063
protein coding gene Chr17:34738953-34745577 (-)
PWK/PhJ MGP_PWKPhJ_G0022584
protein coding gene Chr17:32199013-32205671 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022404
protein coding gene Chr17:32749223-32755958 (-)
WSB/EiJ MGP_WSBEiJ_G0022900
protein coding gene Chr17:34858032-34864653 (-)



Homology
more
  • Human Ortholog
    LY6G6D, lymphocyte antigen 6 family member G6D
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LY6G6D, lymphocyte antigen 6 family member G6D
  • Synonyms
    C6orf23, G6D, LY6-D, MEGT1, NG25
  • Links
    NCBI Gene ID: 58530
    neXtProt AC: NX_O95868
    UniProt: O95868

  • Chr Location
    6p21.33; chr6:31715348-31717919 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
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    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000073413 Ensembl Gene Model | MGI Sequence Detail 6623 C57BL/6J ±  kb
    transcript ENSMUST00000007259 Ensembl | MGI Sequence Detail 546 Not Applicable  
    polypeptide ENSMUSP00000007259 Ensembl | MGI Sequence Detail 135 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 13
      Genomic 1
      cDNA 9
      Primer pair 2
      Other 1

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:2442450
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 1
      Gene Ontology 6
      Phenotypes 9
    • Earliest
      J:63110 Allcock RJ, et al., The mouse as a model for the effects of MHC genes on human disease. Immunol Today. 2000 Jul;21(7):328-32
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    12/10/2024
    MGI 6.24
    The Jackson Laboratory