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Rasa2 Gene Detail
Summary
  • Symbol
    Rasa2
  • Name
    RAS p21 protein activator 2
  • Synonyms
    5430433H21Rik, GAP1m
  • Feature Type
    protein coding gene
  • IDs
    MGI:2149960
    NCBI Gene: 114713
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:96421353-96513665 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 50.66 cM, cytoband E4
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2600 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2149960
 protein coding gene Chr9:96421353-96513670 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035145
 protein coding gene Chr9:97743733-97844550 (-)
A/J MGP_AJ_G0035127
 protein coding gene Chr9:94330149-94421386 (-)
AKR/J MGP_AKRJ_G0035058
 protein coding gene Chr9:96636043-96728764 (-)
BALB/cJ MGP_BALBcJ_G0035119
 protein coding gene Chr9:94012263-94104283 (-)
C3H/HeJ MGP_C3HHeJ_G0034829
 protein coding gene Chr9:97036089-97131737 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035639
 protein coding gene Chr9:100545490-100650930 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032539
 protein coding gene Chr9:92155513-92235537 (-)
CAST/EiJ MGP_CASTEiJ_G0034141
 protein coding gene Chr9:96812993-96909293 (-)
CBA/J MGP_CBAJ_G0034797
 protein coding gene Chr9:104042010-104141618 (-)
DBA/2J MGP_DBA2J_G0034959
 protein coding gene Chr9:93850568-93942815 (-)
FVB/NJ MGP_FVBNJ_G0034907
 protein coding gene Chr9:92698195-92790490 (-)
LP/J MGP_LPJ_G0035038
 protein coding gene Chr9:98010996-98105056 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034946
 protein coding gene Chr9:106033280-106131813 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035661
 protein coding gene Chr9:96871041-96962295 (-)
PWK/PhJ MGP_PWKPhJ_G0033848
 protein coding gene Chr9:94026087-94119815 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033683
 protein coding gene Chr9:96919647-97011931 (-)
WSB/EiJ MGP_WSBEiJ_G0034261
 protein coding gene Chr9:96729072-96823155 (-)



Homology
more
  • Human Ortholog
    RASA2, RAS p21 protein activator 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RASA2, RAS p21 protein activator 2
  • Synonyms
    GAP1M
  • Links
    NCBI Gene ID: 5922
    neXtProt AC: NX_Q15283
    UniProt: Q15283

  • Chr Location
    3q23; chr3:141487027-141615344 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human RASA2 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    715
  • Tissues
    6
  • cDNA Data
    22
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 114713 NCBI Gene Model | MGI Sequence Detail 92313 C57BL/6J ±  kb
transcript NM_053268 RefSeq | MGI Sequence Detail 5699 Not Specified  
polypeptide P58069 UniProt | EBI | MGI Sequence Detail 847 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 24
    cDNA 23
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:1918644, MGI:2142946, MGI:2143226
References
more
  • Summaries
    All 39
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:34521 Fukuda M, et al., Structure-function relationships of the mouse Gap1m. Determination of the inositol 1,3,4,5-tetrakisphosphate-binding domain. J Biol Chem. 1996 Aug 2;271(31):18838-42
  • Latest
    J:215487 Thompson CL, et al., A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory